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Elgemtumab (anti-ERBB3) - Primary antibody, specific to ERBB3, Human IgG1, INHIBITOR of Receptor tyrosine-protein kinase erbB-3 inhibitor, INHIBITOR of Receptor tyrosine-protein kinase erbB-3 inhibitor

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab182826
Grouped product items
SKU Size
Availability
Price Qty
Ab182826-100μg
100μg
10
$89.90
Ab182826-1mg
1mg
4
$419.90
Ab182826-5mg
5mg
1
$1,089.90
Ab182826-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,749.90

Purity≥95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Elgemtumab (anti-ERBB3) - Primary antibody, specific to ERBB3, Human IgG1, INHIBITOR of Receptor tyrosine-protein kinase erbB-3 inhibitor
Synonyms c erbB 3 antibody | c erbB3 antibody | Erb b2 receptor tyrosine kinase 3 antibody | ErbB 3 antibody | ERBB3 antibody | ERBB3 protein antibody | erbB3 S antibody | ERBB3_HUMAN antibody | Glial growth factor receptor antibody | HER 3 antibody | HER3 antibod
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity ERBB3
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action INHIBITOR of Receptor tyrosine-protein kinase erbB-3 inhibitor
Product Description

Elgemtumab (anti-ERBB3) is a fully human IgG monoclonal antibody. Elgemtumab (anti-ERBB3) can specifically bind to HER3, block ligand-dependent and independent HER3 signal transduction and cell proliferation, and has good anti-tumor potential.
Purity
≥95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 26.4 kDa (Light Chain) & 50.5 kDa (Heavy Chain), under reducing conditions; 205.6 kDa, under non-reducing conditions.
Purification Method Protein A purified
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1512559-37-3

Associated Targets(Human)

ERBB3 Tclin Receptor tyrosine-protein kinase erbB-3 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Elgemtumab (anti-ERBB3) (Ab182826) - Flow Cytometry
Flow Cytometry analysis of A431 cells labelling ERBB3 (red) with Elgemtumab (anti-ERBB3) (Ab182826). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Elgemtumab (anti-ERBB3) (Ab182826) - ELISA
Immobilized Recombinant Human ErbB3/HER3 protein (rp170123) at 1.0 μg/mL can bind Elgemtumab (anti-ERBB3) (Ab182826) with the EC50 of 31.89 ng/mL.

Elgemtumab (anti-ERBB3) (Ab182826) - SEC
The purity of Elgemtumab (anti-ERBB3) (Ab182826) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0505863 Certificate of Analysis May 21, 2024 Ab182826
ZJ24F0505864 Certificate of Analysis May 21, 2024 Ab182826
ZJ24F0505865 Certificate of Analysis May 21, 2024 Ab182826

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