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Barecetamab (anti-ERBB3) - Primary antibody, specific to ERBB3, >95% (SDS-PAGE&SEC), high purity, Human IgG1

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab182928
Grouped product items
SKU Size
Availability
Price Qty
Ab182928-100μg
100μg
10
$109.90
Ab182928-1mg
1mg
4
$519.90
Ab182928-5mg
5mg
1
$1,399.90
Ab182928-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,239.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Barecetamab (anti-ERBB3) - Primary antibody, specific to ERBB3, >95% (SDS-PAGE&SEC), high purity, Human IgG1
Synonyms c erbB 3 antibody | c erbB3 antibody | Erb b2 receptor tyrosine kinase 3 antibody | ErbB 3 antibody | ERBB3 antibody | ERBB3 protein antibody | erbB3 S antibody | ERBB3_HUMAN antibody | Glial growth factor receptor antibody | HER 3 antibody | HER3 antibod
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity ERBB3
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Barecetamab (anti-ERBB3) is a fully human anti-ErbB3 monoclonal antibody. Barecetamab (anti-ERBB3) can be used for the research of recurrent/metastatic (R/M) head and neck squamous cell carcinoma (HNSCC).
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG1
Light Chain Type lambda
SDS-PAGE 27.0 kDa (Light Chain) & 50.8 kDa (Heavy Chain), under reducing conditions; 197.7 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95% (SDS-PAGE&SEC)
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 2275727-74-5

Associated Targets(Human)

ERBB3 Tclin Receptor tyrosine-protein kinase erbB-3 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Barecetamab (anti-ERBB3) (Ab182928) - Flow Cytometry
Flow Cytometry analysis of MCF-7 cells labelling ERBB3 (red) with Barecetamab (anti-ERBB3) (Ab182928). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Barecetamab (anti-ERBB3) (Ab182928) - Flow Cytometry
Flow Cytometry analysis of A431 cells labelling ERBB3 (red) with Barecetamab (anti-ERBB3) (Ab182928). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Barecetamab (anti-ERBB3) (Ab182928) - ELISA
Immobilized Recombinant Human ErbB3/HER3 protein (rp170123) at 1.0 μg/mL can bind Barecetamab (anti-ERBB3) (Ab182928) with the EC50 of 14.55 ng/mL.

Barecetamab (anti-ERBB3) (Ab182928) - ELISA
Immobilized Recombinant Human ErbB3/HER3 protein (rp170123) at 1.0 μg/mL can bind Barecetamab (anti-ERBB3) (Ab182928) with the EC50 of 14.55 ng/mL.

Barecetamab (anti-ERBB3) (Ab182928) - SEC
The purity of Barecetamab (anti-ERBB3) (Ab182928) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0505668 Certificate of Analysis May 16, 2024 Ab182928
ZJ24F0505667 Certificate of Analysis May 16, 2024 Ab182928
ZJ24F0505666 Certificate of Analysis May 16, 2024 Ab182928

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