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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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L129221-5g
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5g |
≥10
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$15.90
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L129221-25g
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25g |
≥10
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$53.90
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L129221-100g
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100g |
9
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$148.90
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L129221-500g
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500g |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
|
$444.90
|
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Voltage gated Na + channel blocker
| Synonyms | Lidocaine (USP:INN:BAN:JAN) | LIDOCAINE COMPONENT OF ORAQIX | ORAQIX COMPONENT LIDOCAINE | 2',6'-Acetoxylidide, 2-(diethylamino)- | Gravocain | LIDOCAINE (USP MONOGRAPH) | Lidocaine (VAN) | LIDOCAINE [USP-RS] | Lidocainum | Solcain | Lignocaine | NSC 4003 |
|---|---|
| Specifications & Purity | Moligand™, ≥99% |
| Biochemical and Physiological Mechanisms | Lidocaine is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. Lidocaine is also an anasthetic and class Ib antiarrhythmic agent. This compund is known to block voltage-gated sodium channels in the inactivated state. Lid |
| Storage Temp | Store at 2-8°C,Protected from light,Argon charged |
| Shipped In |
Wet ice This product requires cold chain shipping. Ground and other economy services are not available. |
| Grade | Moligand™ |
| Action Type | BLOCKER, CHANNEL BLOCKER |
| Mechanism of action | Sodium channel alpha subunit blocker |
| Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
| Product Description |
Lidocaine (Alphacaine) is an amide local anesthetic with anti-inflammatory properties in vitro and in vivo. It has this functions perhaps due to an attenuation of intracellular adhesion molecule-1 (ICAM-1), pro-inflammatory cytokines, and reduction of neutrophils influx.
|
Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Class | Benzene and substituted derivatives |
| Subclass | Xylenes |
| Intermediate Tree Nodes | Not available |
| Direct Parent | m-Xylenes |
| Alternative Parents | Trialkylamines Propargyl-type 1,3-dipolar organic compounds Carboximidic acids Organopnictogen compounds Organooxygen compounds Hydrocarbon derivatives |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | M-xylene - Tertiary aliphatic amine - Tertiary amine - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Carboximidic acid derivative - Carboximidic acid - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Amine - Aromatic homomonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as m-xylenes. These are aromatic compounds that contain a m-xylene moiety, which is a monocyclic benzene carrying exactly two methyl groups at the 1- and 3-positions. |
| External Descriptors | tertiary amino compound - monocarboxylic acid amide - benzenes |
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| ALogP | 2.3 |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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| Pubchem Sid | 504750696 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504750696 |
| IUPAC Name | 2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide |
| INCHI | InChI=1S/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17) |
| InChIKey | NNJVILVZKWQKPM-UHFFFAOYSA-N |
| Smiles | CCN(CC)CC(=O)NC1=C(C=CC=C1C)C |
| Isomeric SMILES | CCN(CC)CC(=O)NC1=C(C=CC=C1C)C |
| WGK Germany | 3 |
| RTECS | AN7525000 |
| Molecular Weight | 234.34 |
| Beilstein | 12(4)2538 |
| Reaxy-Rn | 2215784 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2215784&ln= |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Dec 16, 2024 | L129221 | |
| Certificate of Analysis | Dec 16, 2024 | L129221 | |
| Certificate of Analysis | Dec 16, 2024 | L129221 | |
| Certificate of Analysis | Dec 13, 2024 | L129221 | |
| Certificate of Analysis | Dec 13, 2024 | L129221 | |
| Certificate of Analysis | Dec 13, 2024 | L129221 | |
| Certificate of Analysis | Dec 13, 2024 | L129221 | |
| Certificate of Analysis | Aug 20, 2024 | L129221 | |
| Certificate of Analysis | Aug 20, 2024 | L129221 | |
| Certificate of Analysis | Aug 20, 2024 | L129221 | |
| Certificate of Analysis | Aug 20, 2024 | L129221 | |
| Certificate of Analysis | May 20, 2024 | L129221 | |
| Certificate of Analysis | May 20, 2024 | L129221 | |
| Certificate of Analysis | Apr 10, 2024 | L129221 | |
| Certificate of Analysis | Apr 10, 2024 | L129221 | |
| Certificate of Analysis | Apr 10, 2024 | L129221 | |
| Certificate of Analysis | Apr 10, 2024 | L129221 | |
| Certificate of Analysis | Mar 21, 2024 | L129221 | |
| Certificate of Analysis | Mar 21, 2024 | L129221 | |
| Certificate of Analysis | Mar 21, 2024 | L129221 | |
| Certificate of Analysis | Jul 18, 2023 | L129221 | |
| Certificate of Analysis | Jul 18, 2023 | L129221 | |
| Certificate of Analysis | Jul 18, 2023 | L129221 | |
| Certificate of Analysis | Jul 07, 2023 | L129221 | |
| Certificate of Analysis | Jul 07, 2023 | L129221 | |
| Certificate of Analysis | Jul 07, 2023 | L129221 | |
| Certificate of Analysis | Sep 21, 2022 | L129221 | |
| Certificate of Analysis | Jul 11, 2022 | L129221 | |
| Certificate of Analysis | Jun 16, 2022 | L129221 | |
| Certificate of Analysis | Jun 16, 2022 | L129221 | |
| Certificate of Analysis | May 11, 2022 | L129221 |
| Solubility | Soluble in ethanol (50 mg/ml), water (9 mg/ml at 25 °C), methanol, DMSO (47 mg/ml at 25 °C), and chloroform.Soluble in chloroform, benzene, alcohol, and ether |
|---|---|
| Sensitivity | air & light sensitive |
| Boil Point(°C) | 182 °C/4 mmHg |
| Melt Point(°C) | 69 °C |
| Molecular Weight | 234.340 g/mol |
| XLogP3 | 2.300 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 5 |
| Exact Mass | 234.173 Da |
| Monoisotopic Mass | 234.173 Da |
| Topological Polar Surface Area | 32.299 Ų |
| Heavy Atom Count | 17 |
| Formal Charge | 0 |
| Complexity | 228.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
Starting at $70.90
Starting at $3,339.90
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