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Lampalizumab (anti-Complement Factor D) - Primary antibody, specific to CFD, >95%, high purity, Human IgG1, Antibody of complement factor D, Antibody of complement factor D

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human,Rabbit
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab175571
Grouped product items
SKU Size
Availability
Price Qty
Ab175571-100μg
100μg
10
$109.90
Ab175571-1mg
1mg
4
$519.90
Ab175571-5mg
5mg
1
$1,399.90
Ab175571-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,239.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Lampalizumab (anti-Complement Factor D) - Primary antibody, specific to CFD, >95%, high purity, Human IgG1, Antibody of complement factor D
Synonyms Adipsin antibody | Adipsin/complement factor D antibody | Adn antibody | C3 convertase activator antibody | CFAD_HUMAN antibody | CFD antibody | Complement factor D antibody | complement factor D preproprotein antibody | D component of complement antibody
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity CFD
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action Antibody of complement factor D
Product Description

Lampalizumab (anti-Complement Factor D) is a humanised monoclonal antibody targeting complement Factor D in the alternative complement pathway. Lampalizumab (anti-Complement Factor D) binds an exosite and sterically blocks Factor B access to the active site. Lampalizumab (anti-Complement Factor D) can be used for age-related macular degeneration (AMD) research.

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 25.7 kDa (Light Chain) & 50.8 kDa (Heavy Chain), under reducing conditions; 180.0 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1278466-20-8

Associated Targets(Human)

CFD Tchem Complement factor D (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

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Lampalizumab (anti-Complement Factor D) (Ab175571) - SEC
The purity of Lampalizumab (anti-Complement Factor D) (Ab175571) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0405069 Certificate of Analysis Apr 30, 2024 Ab175571
ZJ24F0405068 Certificate of Analysis Apr 30, 2024 Ab175571
ZJ24F0405067 Certificate of Analysis Apr 30, 2024 Ab175571

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