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Lacnotuzumab (anti-M-CSF) - Primary antibody, specific to CSF1, >95%, high purity, Human IgG1

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab177849
Grouped product items
SKU Size
Availability
Price Qty
Ab177849-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$109.90
Ab177849-1mg
1mg
5
$519.90
Ab177849-5mg
5mg
1
$1,399.90
Ab177849-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,239.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Lacnotuzumab (anti-M-CSF) - Primary antibody, specific to CSF1, >95%, high purity, Human IgG1
Synonyms CSF-1 | Lanimostim | MCSF | M-CSF
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity CSF1
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Lacnotuzumab (anti-M-CSF) is a neutralizing humanized IgG1/κ monoclonal antibody targeting CSF-1 that prevents CSF-1 from activating the CSF-1R. Lacnotuzumab can be used for the research of pigmented villonodular synovitis.

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 144.8 kDa
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1831128-32-5

Associated Targets(Human)

CSF1 Tbio Macrophage colony-stimulating factor 1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Lacnotuzumab (anti-M-CSF) (Ab177849) - ELISA
Immobilized Recombinant Human M-CSF Protein (rp148618) at 1.0 μg/mL can bind Lacnotuzumab (anti-M-CSF) (Ab177849) with the EC₅₀ of 9.66 ng/mL.

Lacnotuzumab (anti-M-CSF) (Ab177849) - SEC
The purity of Lacnotuzumab (anti-M-CSF) (Ab177849) is more than 95% verified by HPLC.

Lacnotuzumab (anti-M-CSF) (Ab177849) - ELISA
Immobilized Recombinant human M-CSF protein (rp215098) at 1.0 μg/mL can bind Lacnotuzumab (anti-M-CSF) (Ab177849) with the EC₅₀ of 37.0 ng/mL.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F1202009 Certificate of Analysis Dec 13, 2023 Ab177849
ZJ23F1202010 Certificate of Analysis Dec 13, 2023 Ab177849

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