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Ras
KRAS G12D inhibitor 1 - 98%, high purity , CAS No.2621928-43-4

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KRAS G12D inhibitor 1 - 98%, high purity , CAS No.2621928-43-4

COA

Grade & Purity:

≥98%

Cas Number: 2621928-43-4
Molecular Weight: 582.64

In stock

Item Number

K649425

Grouped product items
SKU	Size	Availability	Price	Qty
K649425-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,500.90
K649425-10mg	10mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,550.90

View related series

G Protein Related (287) GPCR/G Protein (3172) KRAS (55) Ras (143)

Basic Description

Specifications & Purity	≥98%
Biochemical and Physiological Mechanisms	KRAS G12D inhibitor 1 (example 243) is a KRAS G12D inhibitor, with an IC 50 of 0.8 nM for KRAS G12D-mediated ERK phosphorylation.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Product Description	KRAS G12D inhibitor 1 (example 243) is a KRAS G12D inhibitor, with an IC 50 of 0.8 nM for KRAS G12D-mediated ERK phosphorylation Form:Solid IC50& Target:IC50: 0.8 nM (KRAS G12D-mediated ERK phosphorylation)

Names and Identifiers

Smiles	OC1=CC(C2=C(F)C3=NC(OC[C@@]45CCCN4C[C@H](F)C5)=NC(N6C[C@H]7N[C@H](CC7)C6)=C3C=N2)=C8C(C#C)=CC=CC8=C1
Molecular Weight	582.64

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Chemical and Physical Properties

Solubility	DMSO : 55 mg/mL (94.40 mM; Need ultrasonic)

Documents & Articles

KRAS Inhibitors — The "Undruggable Target"? A Thing of the Past

Categories: Technical articles

Tags:

KRAS KRAS-targeted therapy RAS signaling pathway

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