Articles by tag "RAS signaling pathway"

1. KRAS Inhibitors — The "Undruggable Target"? A Thing of the Past
   posted this at Jun 9, 2025

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   KRAS (Kirsten Rat Sarcoma Viral Oncogene Homolog) is a key member of the RAS family. Mutations in KRAS are among the most common oncogenic drivers in several malignancies, including non-small cell lung cancer (NSCLC), pancreatic cancer, and colorectal cancer. It is estimated that KRAS mutations ...