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Jr-141 (anti-TfR) - Primary antibody, specific to TFRC, Human IgG1

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human,Mouse,Rhesus monkey
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab209906
Grouped product items
SKU Size
Availability
Price Qty
Ab209906-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$109.90
Ab209906-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$509.90
Ab209906-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,399.90
Ab209906-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,299.90

Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Jr-141 (anti-TfR) - Primary antibody, specific to TFRC, Human IgG1
Synonyms CD 71 antibody | CD71 antibody | CD71 antigen antibody | IMD46 antibody | OTTHUMP00000208523 antibody | OTTHUMP00000208524 antibody | OTTHUMP00000208525 antibody | p90 antibody | sTfR antibody | T9 antibody | TFR 1 antibody | TfR antibody | TfR1 antibody
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Biochemical and Physiological Mechanisms Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface wi
Host species Human
Specificity TFRC
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Jr-141 (anti-TfR) is an antibody targeting human transferrin receptor (hTfR). It can be used in treatment of patients with mucopolysaccharidosis II (MPS II) and CNS disorders.

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 146.02 kDa
Purification Method Protein A purified
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 2140211-48-7

Associated Targets(Human)

TFRC Tclin Transferrin receptor protein 1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
TFRC Tclin Transferrin receptor protein 1 (0 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Jr-141 (anti-TfR) (Ab209906) - ELISA
Immobilized Recombinant Human Transferrin R/CD71 protein at 2.0 μg/mL can bind Jr-141 (anti-TfR) (Ab209906) with the EC50 of 275.5 ng/mL.

Jr-141 (anti-TfR) (Ab209906) - SEC
The purity of Jr-141 (anti-TfR) (Ab209906) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

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Solution Calculators

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