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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab176424-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$79.90
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Ab176424-1mg
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1mg |
5
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$389.90
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Ab176424-5mg
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5mg |
1
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$989.90
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Ab176424-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,589.90
|
|
Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Idactamab (anti-SLC1A5) - Primary antibody, specific to SLC1A5, >95%, high purity, Human IgG1 |
|---|---|
| Synonyms | ASCT2 antibody | AAAT antibody | AAAT_HUMAN antibody | ATB(0) antibody | ATBO antibody | Baboon M7 virus receptor antibody | FLJ31068 antibody | M7V1 antibody | M7VS1 antibody | Neutral amino acid transporter B(0) antibody | R16 antibody | RD114/simian ty |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | SLC1A5 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
Idactamab (anti-SLC1A5) is an IgG1-κ antibody with in vivo activity across a spectrum of hematological malignancies. Idactamab (anti-SLC1A5) can be used for prepare MEDI7247, a potent and specific ADC, targeting ASCT2 (SLC1A5). |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 27.7 kDa (Light Chain) & 51.6 kDa (Heavy Chain), under reducing conditions; 174.2 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 2245205-37-0 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Idactamab (anti-SLC1A5) (Ab176424) - Flow Cytometry
Flow Cytometry analysis of Jurkat cells labelling SLC1A5 (red) with Idactamab (anti-SLC1A5) (Ab176424). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Nov 08, 2023 | Ab176424 | |
| Certificate of Analysis | Nov 08, 2023 | Ab176424 |