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Glenzocimab (anti-GP6) - Primary antibody, specific to GP6, >95%, high purity, Human IgG1, INHIBITOR of Platelet glycoprotein VI (GPVI) inhibitor, INHIBITOR of Platelet glycoprotein VI (GPVI) inhibitor

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab177896
Grouped product items
SKU Size
Availability
Price Qty
Ab177896-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
Ab177896-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$339.90
Ab177896-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$869.90
Ab177896-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,429.90

Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Glenzocimab (anti-GP6) - Primary antibody, specific to GP6, >95%, high purity, Human IgG1, INHIBITOR of Platelet glycoprotein VI (GPVI) inhibitor
Synonyms Glycoprotein 6 | GPVI
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Biochemical and Physiological Mechanisms Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus for
Host species Human
Specificity GP6
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action INHIBITOR of Platelet glycoprotein VI (GPVI) inhibitor
Product Description

Glenzocimab (anti-GP6) is a Fab fragment of humanized anti-GPVI monoclonal antibody. Glenzocimab (anti-GP6) inhibits collagen-induced platelet aggregation. Glenzocimab (anti-GP6) has the potential for the research of acute ischemic stroke.

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 48.29 kDa
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 2101829-58-5

Associated Targets(Human)

GP6 Tchem Platelet glycoprotein VI (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Glenzocimab (anti-GP6) (Ab177896) - ELISA
Immobilized hu-GPVI-ECD-IEGRMD-hFc at 2.0 μg/mL can bind Glenzocimab (anti-GP6) (Ab177896) with the EC ₅₀ of 67.06 ng/mL.

Glenzocimab (anti-GP6) (Ab177896) - SEC
The purity of Glenzocimab (anti-GP6) (Ab177896) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Solution Calculators

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