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Garadacimab (anti-Factor XII) - Primary antibody, specific to F12, >95%, high purity, Human IgG1

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human,Mouse
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab176574
Grouped product items
SKU Size
Availability
Price Qty
Ab176574-100μg
100μg
10
$79.90
Ab176574-1mg
1mg
4
$389.90
Ab176574-5mg
5mg
1
$749.90
Ab176574-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,189.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Garadacimab (anti-Factor XII) - Primary antibody, specific to F12, >95%, high purity, Human IgG1
Synonyms Factor XII antibody | Beta factor XIIa part 1 antibody | Beta factor XIIa part 2 antibody | Coagulation factor XII antibody | Coagulation factor XIIa heavy chain antibody | Coagulation factor XIIa light chain antibody | F12 antibody | F12 deficiency antib
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity F12
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Garadacimab (anti-Factor XII) is a first-in-class, fully human monoclonal antibody targeting activated factor XII (FXIIa). Garadacimab (anti-Factor XII) has the potential for hereditary angioedema research.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG1
Light Chain Type lambdaC2
SDS-PAGE 27.5 kDa (Light Chain) & 52.5 kDa (Heavy Chain), under reducing conditions; 191.9 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 2162134-62-3

Associated Targets(Human)

F12 Tchem Coagulation factor XII (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Garadacimab (anti-Factor XII) (Ab176574) - SEC
The purity of Garadacimab (anti-Factor XII) (Ab176574) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0404322 Certificate of Analysis Apr 10, 2024 Ab176574
ZJ24F0404321 Certificate of Analysis Apr 10, 2024 Ab176574
ZJ24F0404320 Certificate of Analysis Apr 10, 2024 Ab176574

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