Determine the necessary mass, volume, or concentration for preparing a solution.
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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab176073-100μg
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100μg |
10
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$59.90
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Ab176073-1mg
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1mg |
4
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$289.90
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Ab176073-5mg
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5mg |
1
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$749.90
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Ab176073-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$1,189.90
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Flanvotumab (anti-TYRP1) - Primary antibody, specific to TYRP1, >95%, high purity, Human IgG1, OTHER of 5,6-dihydroxyindole-2-carboxylic acid oxidase other |
|---|---|
| Synonyms | 5 antibody | 5,6 dihydroxyindole 2 carboxylic acid oxidase antibody | 6-dihydroxyindole-2-carboxylic acid oxidase antibody | b-PROTEIN antibody | CAS2 antibody | Catalase B antibody | CATB antibody | DHICA oxidase antibody | Glycoprotein 75 antibody | GP7 |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | TYRP1 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | OTHER |
| Mechanism of action | OTHER of 5,6-dihydroxyindole-2-carboxylic acid oxidase other |
| Product Description |
Flanvotumab (anti-TYRP1) is a human monoclonal antibody targeting to tyrosinase-related protein (TYRP1), specifically expressed in melanocytes and melanoma cells. Flanvotumab (anti-TYRP1) acts function via natural killing-mediated antibody-dependent cell-mediated cytotoxicity (ADCC). Flanvotumab (anti-TYRP1) has potent anti-tumor activity and good tolerance. |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 26.8 kDa (Light Chain) & 51.0 kDa (Heavy Chain), under reducing conditions; 171.0 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 1188277-05-5 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Flanvotumab (anti-TYRP1) (Ab176073) - SEC
The purity of Flanvotumab (anti-TYRP1) (Ab176073) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Feb 23, 2024 | Ab176073 | |
| Certificate of Analysis | Feb 23, 2024 | Ab176073 | |
| Certificate of Analysis | Feb 23, 2024 | Ab176073 |
Starting at $49.90