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Flanvotumab (anti-TYRP1) - Primary antibody, specific to TYRP1, >95%, high purity, Human IgG1, OTHER of 5,6-dihydroxyindole-2-carboxylic acid oxidase other, OTHER of 5,6-dihydroxyindole-2-carboxylic acid oxidase other

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human,Mouse
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab176073
Grouped product items
SKU Size
Availability
Price Qty
Ab176073-100μg
100μg
10
$59.90
Ab176073-1mg
1mg
4
$289.90
Ab176073-5mg
5mg
1
$749.90
Ab176073-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,189.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Flanvotumab (anti-TYRP1) - Primary antibody, specific to TYRP1, >95%, high purity, Human IgG1, OTHER of 5,6-dihydroxyindole-2-carboxylic acid oxidase other
Synonyms 5 antibody | 5,6 dihydroxyindole 2 carboxylic acid oxidase antibody | 6-dihydroxyindole-2-carboxylic acid oxidase antibody | b-PROTEIN antibody | CAS2 antibody | Catalase B antibody | CATB antibody | DHICA oxidase antibody | Glycoprotein 75 antibody | GP7
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity TYRP1
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type OTHER
Mechanism of action OTHER of 5,6-dihydroxyindole-2-carboxylic acid oxidase other
Product Description

Flanvotumab (anti-TYRP1) is a human monoclonal antibody targeting to tyrosinase-related protein (TYRP1), specifically expressed in melanocytes and melanoma cells. Flanvotumab (anti-TYRP1) acts function via natural killing-mediated antibody-dependent cell-mediated cytotoxicity (ADCC). Flanvotumab (anti-TYRP1) has potent anti-tumor activity and good tolerance.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 26.8 kDa (Light Chain) & 51.0 kDa (Heavy Chain), under reducing conditions; 171.0 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1188277-05-5

Associated Targets(Human)

TYRP1 Tbio 5,6-dihydroxyindole-2-carboxylic acid oxidase (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Flanvotumab (anti-TYRP1) (Ab176073) - SEC
The purity of Flanvotumab (anti-TYRP1) (Ab176073) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0202867 Certificate of Analysis Feb 23, 2024 Ab176073
ZJ24F0202868 Certificate of Analysis Feb 23, 2024 Ab176073
ZJ24F0202866 Certificate of Analysis Feb 23, 2024 Ab176073

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