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Ficlatuzumab (anti-HGF) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to HGF, >95%, high purity, Human IgG1, INHIBITOR of Hepatocyte growth factor inhibitor, INHIBITOR of Hepatocyte growth factor inhibitor

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab170563
Grouped product items
SKU Size
Availability
Price Qty
Ab170563-100μg
100μg
10
$69.90
Ab170563-1mg
1mg
4
$327.90
Ab170563-5mg
5mg
1
$837.90
Ab170563-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,317.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Ficlatuzumab (anti-HGF) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to HGF, >95%, high purity, Human IgG1, INHIBITOR of Hepatocyte growth factor inhibitor
Synonyms Hepatopoietin-A | Scatter factor | SF
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity HGF
Application ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR)
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action INHIBITOR of Hepatocyte growth factor inhibitor
Product Description

Ficlatuzumab is a monoclonal antibody (McAb) targeting human hepatocyte growth factor (HGF). Ficlatuzumab blocks the activation of the HGF/c-Met signaling pathway, and inhibits c-Met receptor-mediated cancer cell proliferation, migration, and invasion.

Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Antibody Type Primary antibody
Clonality Recombinant
Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 27.6 kDa (Light Chain) & 50.8 kDa (Heavy Chain), under reducing conditions; 178.7 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Source CHO supernatant
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1174900-84-5

Associated Targets(Human)

HGF Tchem Hepatocyte growth factor (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Ficlatuzumab (anti-HGF) (Ab170563) - ELISA
Immobilized Recombinant human HGF protein (rp156180) at 1.0 μg/mL can bind Ficlatuzumab (anti-HGF) (Ab170563) with the EC₅₀ of 45.64 ng/mL.

Ficlatuzumab (anti-HGF) (Ab170563) - SEC
The purity of Ficlatuzumab (anti-HGF) (Ab170563) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0303072 Certificate of Analysis Mar 08, 2024 Ab170563
ZJ24F0303071 Certificate of Analysis Mar 08, 2024 Ab170563
ZJ24F0303070 Certificate of Analysis Mar 08, 2024 Ab170563

Citations of This Product

1. Yang Shu, Rong Xue, Yiru Gao, Wenxin Zhang, Jianhua Wang.  (2023)  A thermo-responsive hydrogel loaded with an ionic liquid microemulsion for transdermal delivery of methotrexate.  Journal of Materials Chemistry B,  11  (24): (5494-5502). 
2. Shanmeiyu Zhang, Yanyan Zhang, Chongchong Wu, Hui Yang, Qiqi Zhang, Fuyi Wang, Jingyi Wang, Ian Gates, Jinben Wang.  (2021)  A Facile Strategy to Prepare Small Water Clusters via Interacting with Functional Molecules.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,  22  (15): (8250). 
3. Xie Zongliang, Zhang Xiayu, Wang Hailan, Huang Cheng, Sun Haodong, Dong Mengyang, Ji Lei, An Zhongfu, Yu Tao, Huang Wei.  (2021)  Wide-range lifetime-tunable and responsive ultralong organic phosphorescent multi-host/guest system.  Nature Communications,  12  (1): (1-8). 
4. Lanlan Wei, Dongrui Zhou, Xuejun Kang.  (2021)  Electrospinning as a novel strategy for the encapsulation of living probiotics in polyvinyl alcohol/silk fibroin.  Innovative Food Science & Emerging Technologies,  71  (102726). 
5. Huang Jiming, Huang Ding, Zeng Fanbao, Ma Long, Wang Zhengbang.  (2021)  Photocatalytic MOF fibrous membranes for cyclic adsorption and degradation of dyes.  JOURNAL OF MATERIALS SCIENCE,  56  (4): (3127-3139). 
6. Xiu-Qing Qiao, Zhen-Wei Zhang, Qiu-Hao Li, Dongfang Hou, Qichun Zhang, Jian Zhang, Dong-Sheng Li, Pingyun Feng, Xianhui Bu.  (2018)  In situ synthesis of n–n Bi2MoO6 & Bi2S3 heterojunctions for highly efficient photocatalytic removal of Cr(VI).  Journal of Materials Chemistry A,  (45): (22580-22589). 
7. Yiwen Zhang, Zixuan Tang, Liyun Chen, Min Yang, Yating Zeng, Xujue Bai, Bingna Zhang, Jianda Zhou, Wancong Zhang, Shijie Tang.  (2025)  Intelligent sequential degradation hydrogels by releasing bimetal-phenolic for enhanced diabetic wound healing.  JOURNAL OF CONTROLLED RELEASE,  378  (961). 

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