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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab170563-100μg
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100μg |
10
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$69.90
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Ab170563-1mg
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1mg |
4
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$327.90
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Ab170563-5mg
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5mg |
1
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$837.90
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Ab170563-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$1,317.90
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Ficlatuzumab (anti-HGF) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to HGF, >95%, high purity, Human IgG1, INHIBITOR of Hepatocyte growth factor inhibitor |
|---|---|
| Synonyms | Hepatopoietin-A | Scatter factor | SF |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | HGF |
| Application | ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of Hepatocyte growth factor inhibitor |
| Product Description |
Ficlatuzumab is a monoclonal antibody (McAb) targeting human hepatocyte growth factor (HGF). Ficlatuzumab blocks the activation of the HGF/c-Met signaling pathway, and inhibits c-Met receptor-mediated cancer cell proliferation, migration, and invasion. Purity |
| Antibody Type | Primary antibody |
|---|---|
| Clonality | Recombinant |
| Isotype | Human IgG1 |
| Light Chain Type | kappa |
| SDS-PAGE | 27.6 kDa (Light Chain) & 50.8 kDa (Heavy Chain), under reducing conditions; 178.7 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Source | CHO supernatant |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 1174900-84-5 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Ficlatuzumab (anti-HGF) (Ab170563) - ELISA
Immobilized Recombinant human HGF protein (rp156180) at 1.0 μg/mL can bind Ficlatuzumab (anti-HGF) (Ab170563) with the EC₅₀ of 45.64 ng/mL.
Ficlatuzumab (anti-HGF) (Ab170563) - SEC
The purity of Ficlatuzumab (anti-HGF) (Ab170563) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Mar 08, 2024 | Ab170563 | |
| Certificate of Analysis | Mar 08, 2024 | Ab170563 | |
| Certificate of Analysis | Mar 08, 2024 | Ab170563 |
Starting at $109.90
Starting at $59.90
| 1. Yang Shu, Rong Xue, Yiru Gao, Wenxin Zhang, Jianhua Wang. (2023) A thermo-responsive hydrogel loaded with an ionic liquid microemulsion for transdermal delivery of methotrexate. Journal of Materials Chemistry B, 11 (24): (5494-5502). |
| 2. Shanmeiyu Zhang, Yanyan Zhang, Chongchong Wu, Hui Yang, Qiqi Zhang, Fuyi Wang, Jingyi Wang, Ian Gates, Jinben Wang. (2021) A Facile Strategy to Prepare Small Water Clusters via Interacting with Functional Molecules. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22 (15): (8250). |
| 3. Xie Zongliang, Zhang Xiayu, Wang Hailan, Huang Cheng, Sun Haodong, Dong Mengyang, Ji Lei, An Zhongfu, Yu Tao, Huang Wei. (2021) Wide-range lifetime-tunable and responsive ultralong organic phosphorescent multi-host/guest system. Nature Communications, 12 (1): (1-8). |
| 4. Lanlan Wei, Dongrui Zhou, Xuejun Kang. (2021) Electrospinning as a novel strategy for the encapsulation of living probiotics in polyvinyl alcohol/silk fibroin. Innovative Food Science & Emerging Technologies, 71 (102726). |
| 5. Huang Jiming, Huang Ding, Zeng Fanbao, Ma Long, Wang Zhengbang. (2021) Photocatalytic MOF fibrous membranes for cyclic adsorption and degradation of dyes. JOURNAL OF MATERIALS SCIENCE, 56 (4): (3127-3139). |
| 6. Xiu-Qing Qiao, Zhen-Wei Zhang, Qiu-Hao Li, Dongfang Hou, Qichun Zhang, Jian Zhang, Dong-Sheng Li, Pingyun Feng, Xianhui Bu. (2018) In situ synthesis of n–n Bi2MoO6 & Bi2S3 heterojunctions for highly efficient photocatalytic removal of Cr(VI). Journal of Materials Chemistry A, 6 (45): (22580-22589). |
| 7. Yiwen Zhang, Zixuan Tang, Liyun Chen, Min Yang, Yating Zeng, Xujue Bai, Bingna Zhang, Jianda Zhou, Wancong Zhang, Shijie Tang. (2025) Intelligent sequential degradation hydrogels by releasing bimetal-phenolic for enhanced diabetic wound healing. JOURNAL OF CONTROLLED RELEASE, 378 (961). |