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Fezakinumab (anti-IL-22) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to IL22, >95%, high purity, Human IgG1, INHIBITOR of Interleukin-22 inhibitor, INHIBITOR of Interleukin-22 inhibitor

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human,Rat
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab170546
Grouped product items
SKU Size
Availability
Price Qty
Ab170546-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$59.90
Ab170546-1mg
1mg
5
$267.90
Ab170546-5mg
5mg
1
$627.90
Ab170546-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,017.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Fezakinumab (anti-IL-22) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to IL22, >95%, high purity, Human IgG1, INHIBITOR of Interleukin-22 inhibitor
Synonyms Cytokine Zcyto18 | IL-10-related T-cell-derived-inducible factor | IL-22 | IL-TIF
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity IL22
Application ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR)
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action INHIBITOR of Interleukin-22 inhibitor
Product Description

Fezakinumab is an interleukin-22 (IL-22) monoclonal antibody. Fezakinumab can be used for the research of inflammatory disease, such as psoriasis and rheumatoid arthritis.

Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Antibody Type Primary antibody
Clonality Recombinant
Isotype Human IgG1
Light Chain Type lambdaC2
SDS-PAGE 28.1 kDa (Light Chain) & 53.8 kDa (Heavy Chain), under reducing conditions; 183.3 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Source CHO supernatant
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1007106-86-6

Associated Targets(Human)

IL22 Tbio Interleukin-22 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Fezakinumab (anti-IL-22) (Ab170546) - ELISA
Immobilized Recombinant Human IL-22 Protein at 1 μg/mL can bind Fezakinumab (anti-IL-22) (Ab170546) with the EC₅₀ of 69.72 ng/mL.

Fezakinumab (anti-IL-22) (Ab170546) - SEC
The purity of Fezakinumab (anti-IL-22) (Ab170546) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F1101604 Certificate of Analysis Nov 08, 2023 Ab170546
ZJ23F1101605 Certificate of Analysis Nov 08, 2023 Ab170546

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