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Erenumab (anti-CALCRL) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to CALCRL, >95%, high purity, Human IgG2SA, Antibody of CGRP receptor, Antibody of CGRP receptor

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human
  • Isotype: Human IgG2SA
  • Conjugation: Unconjugated
In stock
Item Number
Ab170518
Grouped product items
SKU Size
Availability
Price Qty
Ab170518-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$49.90
Ab170518-1mg
1mg
5
$237.90
Ab170518-5mg
5mg
1
$657.90
Ab170518-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,047.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG2Sa; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Erenumab (anti-CALCRL) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to CALCRL, >95%, high purity, Human IgG2SA, Antibody of CGRP receptor
Synonyms Calcitonin receptor-like receptor | CGRP type 1 receptor
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity CALCRL
Application ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR)
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type ANTAGONIST
Mechanism of action Antibody of CGRP receptor
Product Description

Erenumab is a fully human monoclonal antibody. Erenumab inhibits the calcitonin gene–related peptide (CGRP) receptor. Erenumab can be used for the prevention of episodic migraine.
Purity:>95% (SDS-PAGE&SEC)
Endotoxin Level:< 1.0EU/mg

Product Properties

Antibody Type Primary antibody
Clonality Recombinant
Isotype Human IgG2SA
Light Chain Type lambda
SDS-PAGE 27.7 kDa (Light Chain) & 52.0 kDa (Heavy Chain), under reducing conditions; 175.2 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Source CHO supernatant
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1582205-90-0

Associated Targets(Human)

RAMP1 Tclin Receptor activity-modifying protein 1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
CALCRL Tclin Calcitonin gene-related peptide type 1 receptor (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
CALCRL Tclin Calcitonin gene-related peptide type 1 receptor (1509 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
RAMP1 Tclin Calcitonin-gene-related peptide receptor, CALCRL/RAMP1 (193 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Erenumab (anti-CALCRL) (Ab170518) - SEC
The purity of Erenumab (anti-CALCRL) (Ab170518) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ24F0102480 Certificate of Analysis Jan 18, 2024 Ab170518
ZJ24F0102479 Certificate of Analysis Jan 18, 2024 Ab170518

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