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Emibetuzumab (anti-MET) - Primary antibody, specific to MET, >95%, high purity, Human IgG4SP, INHIBITOR of Hepatocyte growth factor receptor inhibitor, INHIBITOR of Hepatocyte growth factor receptor inhibitor

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human,Rat
  • Isotype: Human IgG4SP
  • Conjugation: Unconjugated
In stock
Item Number
Ab170880
Grouped product items
SKU Size
Availability
Price Qty
Ab170880-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$39.90
Ab170880-1mg
1mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$177.90
Ab170880-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$537.90
Ab170880-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$837.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Emibetuzumab (anti-MET) - Primary antibody, specific to MET, >95%, high purity, Human IgG4SP, INHIBITOR of Hepatocyte growth factor receptor inhibitor
Synonyms AUTS9 antibody | c met antibody | D249 antibody | Hepatocyte growth factor receptor antibody | HGF antibody | HGF receptor antibody | HGF/SF receptor antibody | HGFR antibody | MET antibody | Met proto oncogene antibody | Met proto oncogene tyrosine kinas
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity MET
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action INHIBITOR of Hepatocyte growth factor receptor inhibitor
Product Description

Emibetuzumab (anti-MET) is a humanized bivalent MET antibody (IgG4 type). Emibetuzumab (anti-MET) shows high neutralization and internalization activities, resulting in inhibition of both HGF-dependent and HGF-independent MET pathway activation and tumor growth. Emibetuzumab (anti-MET) can be used in study of cancer.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG4SP
Light Chain Type kappa
SDS-PAGE 26.8 kDa (Light Chain) & 54.3 kDa (Heavy Chain), under reducing conditions; 179.3 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1365287-97-3

Associated Targets(Human)

MET Tclin Hepatocyte growth factor receptor (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Emibetuzumab (anti-MET) (Ab170880) - Flow Cytometry
Flow Cytometry analysis of HepG2 cells labelling MET (red) with Emibetuzumab (anti-MET) (Ab170880). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Emibetuzumab (anti-MET) (Ab170880) - SEC
The purity of Emibetuzumab (anti-MET) (Ab170880) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F1001469 Certificate of Analysis Nov 01, 2023 Ab170880
ZJ23F1001470 Certificate of Analysis Nov 01, 2023 Ab170880

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