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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab170882-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$99.90
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Ab170882-1mg
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1mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$477.90
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Ab170882-5mg
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5mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$1,167.90
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Ab170882-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,857.90
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Eldelumab (anti-CXCL10) - Primary antibody, specific to CXCL10, >95%, high purity, Human IgG1, INHIBITOR of C-X-C motif chemokine 10 inhibitor |
|---|---|
| Synonyms | Interferon gamma induced factor MOB1, mouse, homolog of antibody | Interferon gamma induced protein 10 antibody | 10 kDa interferon gamma induced protein antibody | 10 kDa interferon gamma-induced protein antibody | C X C motif chemokine 10 antibody | C7 |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | CXCL10 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of C-X-C motif chemokine 10 inhibitor |
| Product Description |
Eldelumab (anti-CXCL10) is a humanised anti-CXCL10 (IP-10) monoclonal antibody (IgG1 type). Eldelumab (anti-CXCL10) selectively binds to CXCL10 and blocks CXCL10-induced calcium flux and cell migration. Eldelumab (anti-CXCL10) can be used in studies of autoimmune and auto-inflammatory diseases such as rheumatoid arthritis, ulcerative colitis and crohn's disease. |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 27.1 kDa (Light Chain) & 53.9 kDa (Heavy Chain), under reducing conditions; 182.8 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 946414-98-8 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Eldelumab (anti-CXCL10) (Ab170882) - SEC
The purity of Eldelumab (anti-CXCL10) (Ab170882) is more than 95% verified by HPLC.
Eldelumab (anti-CXCL10) (Ab170882) - ELISA
Immobilized Recombinant Human CXCL10/IP-10 Protein (rp170434) at 1.0 μg/mL can bind Eldelumab (anti-CXCL10) (Ab170882) with the EC₅₀ of 268.7 ng/mL.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Nov 01, 2023 | Ab170882 | |
| Certificate of Analysis | Nov 01, 2023 | Ab170882 |
Starting at $109.90