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Eldelumab (anti-CXCL10) - Primary antibody, specific to CXCL10, >95%, high purity, Human IgG1, INHIBITOR of C-X-C motif chemokine 10 inhibitor, INHIBITOR of C-X-C motif chemokine 10 inhibitor

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human,Rhesus monkey
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab170882
Grouped product items
SKU Size
Availability
Price Qty
Ab170882-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$99.90
Ab170882-1mg
1mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$477.90
Ab170882-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$1,167.90
Ab170882-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,857.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Eldelumab (anti-CXCL10) - Primary antibody, specific to CXCL10, >95%, high purity, Human IgG1, INHIBITOR of C-X-C motif chemokine 10 inhibitor
Synonyms Interferon gamma induced factor MOB1, mouse, homolog of antibody | Interferon gamma induced protein 10 antibody | 10 kDa interferon gamma induced protein antibody | 10 kDa interferon gamma-induced protein antibody | C X C motif chemokine 10 antibody | C7
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity CXCL10
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action INHIBITOR of C-X-C motif chemokine 10 inhibitor
Product Description

Eldelumab (anti-CXCL10) is a humanised anti-CXCL10 (IP-10) monoclonal antibody (IgG1 type). Eldelumab (anti-CXCL10) selectively binds to CXCL10 and blocks CXCL10-induced calcium flux and cell migration. Eldelumab (anti-CXCL10) can be used in studies of autoimmune and auto-inflammatory diseases such as rheumatoid arthritis, ulcerative colitis and crohn's disease.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 27.1 kDa (Light Chain) & 53.9 kDa (Heavy Chain), under reducing conditions; 182.8 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 946414-98-8

Associated Targets(Human)

CXCL10 Tbio C-X-C motif chemokine 10 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Eldelumab (anti-CXCL10) (Ab170882) - SEC
The purity of Eldelumab (anti-CXCL10) (Ab170882) is more than 95% verified by HPLC.

Eldelumab (anti-CXCL10) (Ab170882) - ELISA
Immobilized Recombinant Human CXCL10/IP-10 Protein (rp170434) at 1.0 μg/mL can bind Eldelumab (anti-CXCL10) (Ab170882) with the EC₅₀ of 268.7 ng/mL.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F1001471 Certificate of Analysis Nov 01, 2023 Ab170882
ZJ23F1001472 Certificate of Analysis Nov 01, 2023 Ab170882

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