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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab209927-100μg
|
100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$109.90
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Ab209927-1mg
|
1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$509.90
|
|
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Ab209927-5mg
|
5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,399.90
|
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Ab209927-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$2,299.90
|
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Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated
| Product Name | DX-2647 (anti-IGF2) - Primary antibody, specific to IGF2, Human IgG1 |
|---|---|
| Synonyms | C11orf43 antibody | IGF 2 antibody | IGF II antibody | IGF-II antibody | IGF2 antibody | IGF2_HUMAN antibody | IGFII antibody | INSIGF antibody | insulin like growth factor 2 (somatomedin A) antibody | Insulin like Growth Factor 2 antibody | Insulin like |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Biochemical and Physiological Mechanisms | The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development. Preptin undergoes glucose-mediated co-secretion |
| Host species | Human |
| Specificity | IGF2 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
DX-2647 (anti-IGF2) is a human monoclonal antibody against insulin-like growth factor-II (IGF-II) with anti-tumor and anti-proliferative activities. |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 145.78 kDa |
| Purification Method | Protein A purified |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
DX-2647 (anti-IGF2) (Ab209927) - ELISA
Immobilized Recombinant Human IGF2 protein (rp147265) at 1.0 μg/mL can bind DX-2647 (anti-IGF2) (Ab209927) with the EC50 of 114.3 ng/mL.
DX-2647 (anti-IGF2) (Ab209927) - SEC
The purity of DX-2647 (anti-IGF2) (Ab209927) is more than 95% verified by HPLC.