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Dapoxetine - ≥98%, high purity , Serotonin transporter inhibitor, CAS No.119356-77-3, Serotonin transporter inhibitor

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Dapoxetine - ≥98%, high purity , Serotonin transporter inhibitor, CAS No.119356-77-3, Serotonin transporter inhibitor

COA

Grade & Purity:

Moligand™

≥98%

Cas Number: 119356-77-3
Molecular Weight: 305.40
PubChem CID: 71353
PubChem SID: 504754617

In stock

Item Number

D302541

Grouped product items
SKU	Size	Availability	Price
D302541-1g	1g	1	$48.90
D302541-5g	5g	1	$196.90
D302541-25g	25g	1	$687.90

View related series

Neuronal Signaling (3320) Serotonin Transporter (66) SERT Inhibitor (31)

Basic Description

Synonyms	Conadil \| Benzenemethanamine, N,N-dimethyl-alpha-[2-(1-naphthalenyloxy)ethyl]-, (alphaS)- \| Dapoxetine (Free Base) \| N,N-dimethyl-alpha-[2-(1-naphthalenyloxy)ethyl]-Benzenemethanamine \| Sulindac,(S) \| DTXCID1031416 \| CHEBI:135962 \| C21H23NO \| DB04884 \| Da
Specifications & Purity	Moligand™, ≥98%
Biochemical and Physiological Mechanisms	Dapoxetine is capable of blocking recombinant Kv4.3 potassium voltage-gated channels. It is considered as safe
Storage Temp	Store at 2-8°C
Shipped In	Wet ice This product requires cold chain shipping. Ground and other economy services are not available.
Grade	Moligand™
Action Type	INHIBITOR
Mechanism of action	Serotonin transporter inhibitor
Product Description	Product Describtion: Dapoxetine ((+)-(S)-N,N-dimethyl-(α)-[2(1naphthal enyloxy)ethyl]-benzenemethanamine hydrochloride) possess a similar structure as that of fluoxetine. Product Application: Dapoxetine is a serotonin reuptake inhibitor used for the treatment of premature ejaculation.

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - Class Naphthalenes

Kingdom	Organic compounds
Superclass	Benzenoids
Class	Naphthalenes
Subclass	Not available
Intermediate Tree Nodes	Not available
Direct Parent	Naphthalenes
Alternative Parents	Aralkylamines Alkyl aryl ethers Benzene and substituted derivatives Trialkylamines Organopnictogen compounds Hydrocarbon derivatives
Molecular Framework	Aromatic homopolycyclic compounds
Substituents	Naphthalene - Aralkylamine - Alkyl aryl ether - Monocyclic benzene moiety - Tertiary aliphatic amine - Tertiary amine - Ether - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Amine - Aromatic homopolycyclic compound
Description	This compound belongs to the class of organic compounds known as naphthalenes. These are compounds containing a naphthalene moiety, which consists of two fused benzene rings.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Product Properties

ALogP	5.1

Associated Targets(Human)

SLC6A4 Tclin Sodium-dependent serotonin transporter (1 Activities)

Discover Target: SLC6A4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	504754617
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504754617
IUPAC Name	(1S)-N,N-dimethyl-3-naphthalen-1-yloxy-1-phenylpropan-1-amine
INCHI	InChI=1S/C21H23NO/c1-22(2)20(18-10-4-3-5-11-18)15-16-23-21-14-8-12-17-9-6-7-13-19(17)21/h3-14,20H,15-16H2,1-2H3/t20-/m0/s1
InChIKey	USRHYDPUVLEVMC-FQEVSTJZSA-N
Smiles	CN(C)C(CCOC1=CC=CC2=CC=CC=C21)C3=CC=CC=C3
Isomeric SMILES	CN(C)[C@@H](CCOC1=CC=CC2=CC=CC=C21)C3=CC=CC=C3
Molecular Weight	305.40
Reaxy-Rn	13862595
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=13862595&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

9 results found

Lot Number	Certificate Type	Date	Item
G2425346	Certificate of Analysis	Jul 30, 2024	D302541
G2425347	Certificate of Analysis	Jul 30, 2024	D302541
G2425348	Certificate of Analysis	Jul 30, 2024	D302541
G2425349	Certificate of Analysis	Jul 30, 2024	D302541
J2318347	Certificate of Analysis	Oct 24, 2023	D302541
J2318342	Certificate of Analysis	Oct 24, 2023	D302541
J2318343	Certificate of Analysis	Oct 24, 2023	D302541
J2318344	Certificate of Analysis	Oct 24, 2023	D302541
J2318345	Certificate of Analysis	Oct 24, 2023	D302541

Chemical and Physical Properties

Solubility	Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly)
Specific Rotation[α]	+125 to +135°, c = 1 in methanol
Molecular Weight	305.400 g/mol
XLogP3	5.100
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	6
Exact Mass	305.178 Da
Monoisotopic Mass	305.178 Da
Topological Polar Surface Area	12.500 Å²
Heavy Atom Count	23
Formal Charge	0
Complexity	337.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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