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Dapoxetine hydrochloride - ≥98% (HPLC), high purity , CAS No.129938-20-1

1 Citations

COA

Grade & Purity:

≥98%(HPLC)

Cas Number: 129938-20-1
Molecular Weight: 341.87
MDL number: MFCD08272809
PubChem CID: 71352
PubChem SID: 504754616

In stock

Item Number

D129639

Grouped product items
SKU	Size	Availability	Price
D129639-250mg	250mg	2	$14.90
D129639-1g	1g	3	$44.90
D129639-5g	5g	3	$133.90
D129639-25g	25g	3	$469.90
D129639-100g	100g	2	$1,299.90

Potent short-acting SSRI. Kv4.3 channel blocker.

View related series

Neuronal Signaling (3320) Pharmaceutical ingredients (367) Serotonin Transporter (66)

Basic Description

Synonyms	Asulfidine \| Dapoxetine (as hydrochloride) \| Dapoxetine hydrochloride, >=98% (HPLC) \| (1S)-N,N-dimethyl-3-naphthalen-1-yloxy-1-phenylpropan-1-amine;hydrochloride \| CCG-267940 \| D03649 \| LY-210448 hydrochloride;(S)-N,N-dimethyl-1-phenyl-3-(1-naphthalenylox
Specifications & Purity	≥98%(HPLC)
Biochemical and Physiological Mechanisms	Effective selective serotonin reuptake inhibitors (SSRIs); Used to treat premature ejaculation Dapoxetine can block the recombinant Kv4.3 voltage gated potassium channel. Confirmed as a safe therapeutic drug.
Storage Temp	Store at 2-8°C
Shipped In	Wet ice This product requires cold chain shipping. Ground and other economy services are not available.
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Dapoxetine HCl is a short-acting novel selective serotonin reuptake inhibitor A selective serotonin reuptake inhibitor

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Benzenoids
  - Class Naphthalenes

Kingdom	Organic compounds
Superclass	Benzenoids
Class	Naphthalenes
Subclass	Not available
Intermediate Tree Nodes	Not available
Direct Parent	Naphthalenes
Alternative Parents	Aralkylamines Alkyl aryl ethers Benzene and substituted derivatives Trialkylamines Organopnictogen compounds Hydrochlorides Hydrocarbon derivatives
Molecular Framework	Aromatic homopolycyclic compounds
Substituents	Naphthalene - Alkyl aryl ether - Aralkylamine - Monocyclic benzene moiety - Tertiary amine - Tertiary aliphatic amine - Ether - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organopnictogen compound - Organic nitrogen compound - Organic oxygen compound - Amine - Hydrochloride - Aromatic homopolycyclic compound
Description	This compound belongs to the class of organic compounds known as naphthalenes. These are compounds containing a naphthalene moiety, which consists of two fused benzene rings.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

HepG2 (196354 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Mechanism of Action	Action Type	target ID	Target Name	Target Type	Target Organism	Binding Site Name	References

Names and Identifiers

Pubchem Sid	504754616
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504754616
IUPAC Name	(1S)-N,N-dimethyl-3-naphthalen-1-yloxy-1-phenylpropan-1-amine;hydrochloride
INCHI	InChI=1S/C21H23NO.ClH/c1-22(2)20(18-10-4-3-5-11-18)15-16-23-21-14-8-12-17-9-6-7-13-19(17)21;/h3-14,20H,15-16H2,1-2H3;1H/t20-;/m0./s1
InChIKey	IHWDIQRWYNMKFM-BDQAORGHSA-N
Smiles	CN(C)C(CCOC1=CC=CC2=CC=CC=C21)C3=CC=CC=C3.Cl
Isomeric SMILES	CN(C)[C@@H](CCOC1=CC=CC2=CC=CC=C21)C3=CC=CC=C3.Cl
WGK Germany	3
Molecular Weight	341.87
Reaxy-Rn	32311059
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=32311059&ln=

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot Number	Certificate Type	Date	Item
I2219302	Certificate of Analysis	Jul 09, 2024	D129639
I2219301	Certificate of Analysis	Jul 09, 2024	D129639
I2217216	Certificate of Analysis	Jul 05, 2024	D129639
H2402191	Certificate of Analysis	Jun 04, 2024	D129639
H2402192	Certificate of Analysis	Jun 04, 2024	D129639
H2402193	Certificate of Analysis	Jun 04, 2024	D129639
I2122013	Certificate of Analysis	Jul 14, 2023	D129639
F1509083	Certificate of Analysis	Jan 16, 2023	D129639
E2011061	Certificate of Analysis	Apr 13, 2022	D129639
C2222033	Certificate of Analysis	Mar 25, 2022	D129639

Chemical and Physical Properties

Solubility	Soluble in DMSO (68 mg/ml at 25 °C), chloroform, methanol, water (68 mg/ml at 25 °C), and ethanol (68 mg/ml at 25 °C).
Sensitivity	Heat Sensitive；Moisture sensitive
Specific Rotation[α]	125° (C=1,MeOH)
Melt Point(°C)	181 °C
Molecular Weight	341.900 g/mol
XLogP3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	6
Exact Mass	341.155 Da
Monoisotopic Mass	341.155 Da
Topological Polar Surface Area	12.500 Å²
Heavy Atom Count	24
Formal Charge	0
Complexity	337.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	2

Alternative Products

Citations of This Product

How to Cite Aladdin Scientific Products?

1. Yanbo Tian, Liju Tan, Huiru Li, Yu Qiao, Na Wang, Jiangtao Wang. (2025) Preparation of magnetic molecular imprinted polymers based on deep eutectic solvent and its application in the specific adsorption and detection of fluoxetine hydrochloride. REACTIVE & FUNCTIONAL POLYMERS, 207 (106122).

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