Determine the necessary mass, volume, or concentration for preparing a solution.
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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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C102301-1g
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1g |
3
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$19.90
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C102301-5g
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5g |
2
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$54.90
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C102301-25g
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25g |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$159.90
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C102301-100g
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100g |
3
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$514.90
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C102301-500g
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500g |
1
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$1,244.90
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Prototypic H 2 antagonist. I 1 agonist.
| Synonyms | 1-Cyano-2-methyl-3-(2-(((5-methyl-4-imidazolyl)methyl)thio)ethyl)guanidine | Aciloc | CIMETIDINE A | Ulcimet | Cimetag | Cimetidinum | FPF 1002 | Tagamet | Brumetidina | CIMETIDINE [USP MONOGRAPH] | Edalene | SKF 92334 | Tocris-0902 | Ulcedin | 2-Cyano-1- |
|---|---|
| Specifications & Purity | Moligand™, ≥99% |
| Biochemical and Physiological Mechanisms | H2 histamine receptor antagonist; I1 imidazoline receptor agonist; anti-ulcer agent. Blocks cancer metastasis by inhibiting the expression of E-selectin on the surface of endothelial cells, thus blocking tumor cell adhesion.Prototypic H 2 antagonist. Also |
| Storage Temp | Store at 2-8°C |
| Shipped In |
Wet ice This product requires cold chain shipping. Ground and other economy services are not available. |
| Grade | Moligand™ |
| Action Type | ANTAGONIST, INHIBITOR |
| Mechanism of action | Histamine H2 receptor antagonist |
| Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Class | Azoles |
| Subclass | Imidazoles |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Imidazoles |
| Alternative Parents | Heteroaromatic compounds Guanidines Sulfenyl compounds Propargyl-type 1,3-dipolar organic compounds Dialkylthioethers Carboximidamides Azacyclic compounds Organopnictogen compounds Imines Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteromonocyclic compounds |
| Substituents | Imidazole - Heteroaromatic compound - Guanidine - Thioether - Carboximidamide - Sulfenyl compound - Propargyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Dialkylthioether - Azacycle - Organic nitrogen compound - Organopnictogen compound - Imine - Organonitrogen compound - Organosulfur compound - Hydrocarbon derivative - Aromatic heteromonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as imidazoles. These are compounds containing an imidazole ring, which is an aromatic five-member ring with two nitrogen atoms at positions 1 and 3, and three carbon atoms. |
| External Descriptors | imidazoles - guanidines - aliphatic sulfide - nitrile |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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| Pubchem Sid | 504750600 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504750600 |
| IUPAC Name | 1-cyano-2-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine |
| INCHI | InChI=1S/C10H16N6S/c1-8-9(16-7-15-8)5-17-4-3-13-10(12-2)14-6-11/h7H,3-5H2,1-2H3,(H,15,16)(H2,12,13,14) |
| InChIKey | AQIXAKUUQRKLND-UHFFFAOYSA-N |
| Smiles | CC1=C(N=CN1)CSCCNC(=NC)NC#N |
| Isomeric SMILES | CC1=C(N=CN1)CSCCNC(=NC)NC#N |
| WGK Germany | 3 |
| RTECS | MF0035500 |
| Molecular Weight | 252.34 |
| Reaxy-Rn | 807826 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=807826&ln= |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Apr 02, 2025 | C102301 | |
| Certificate of Analysis | Apr 02, 2025 | C102301 | |
| Certificate of Analysis | Apr 02, 2025 | C102301 | |
| Certificate of Analysis | Apr 02, 2025 | C102301 | |
| Certificate of Analysis | Apr 02, 2025 | C102301 | |
| Certificate of Analysis | Jun 26, 2024 | C102301 | |
| Certificate of Analysis | Jun 26, 2024 | C102301 | |
| Certificate of Analysis | May 06, 2023 | C102301 | |
| Certificate of Analysis | Jul 21, 2022 | C102301 | |
| Certificate of Analysis | Jul 21, 2022 | C102301 | |
| Certificate of Analysis | Jul 21, 2022 | C102301 | |
| Certificate of Analysis | Jul 21, 2022 | C102301 | |
| Certificate of Analysis | Jul 21, 2022 | C102301 | |
| Certificate of Analysis | Jul 21, 2022 | C102301 | |
| Certificate of Analysis | Jul 21, 2022 | C102301 | |
| Certificate of Analysis | May 30, 2022 | C102301 | |
| Certificate of Analysis | Apr 26, 2022 | C102301 |
| Solubility | Soluble to 50 mM in water and to 100 mM in DMSO, solubility in HCl (almost transparency). |
|---|---|
| Melt Point(°C) | 141°C |
| Molecular Weight | 252.340 g/mol |
| XLogP3 | 0.400 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 7 |
| Exact Mass | 252.116 Da |
| Monoisotopic Mass | 252.116 Da |
| Topological Polar Surface Area | 114.000 Ų |
| Heavy Atom Count | 17 |
| Formal Charge | 0 |
| Complexity | 296.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
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