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CD45RA Mouse mAb - Primary antibody, specific to CD45RA, Mouse IgG2b

COA COA
    Application:
  • Flow Cytometry
  • Host species: Mouse
  • Reactive species: Human
  • Isotype: Mouse IgG2b
  • Clone Number: HI100
  • Conjugation: Unconjugated
In stock
Item Number
Ab006750
Grouped product items
SKU Size
Availability
 Price Qty
Ab006750-10μg
10μg
1
$16.90
Ab006750-50μg
50μg
4
$39.90
Ab006750-100μg
100μg
3
$69.90
Ab006750-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$619.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

mAb (HI100); Mouse anti Human CD45RA Antibody; Flow; Unconjugated

View related series
Click to view target information: PTPRC
Accession#:P08575 (56) CD45 (68) Flow Cytometry (1158) Gene ID:5788 (52)

Basic Description

Product Name CD45RA Mouse mAb - Primary antibody, specific to CD45RA, Mouse IgG2b
Synonyms EC 3.1.3.48 | L-CA | Leukocyte common antigen | T200
Specifications & Purity Carrier Free, ExactAb™, Validated, See COA
Host species Mouse
Specificity CD45RA
Immunogen Low buoyancy density human lymphocytes
Conjugation Unconjugated
Grade Carrier Free, ExactAb™, Validated
Product Description

Mouse anti Human CD45RA Antibody, Monoclonal (HI100), could be used for Flow and so on.
Application:
Flow: < 0.5 μg/100w cells
Protein Function
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity.

Product Properties

Isotype Mouse IgG2b
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein A purified
Shape Liquid
Concentration See COA
Storage Temp Store at 2-8°C
Shipped In Wet ice
Stability And Storage Shipped at 4°C. Store at 4°C long term (36 months). Upon receipt, it is recommended to aliquot.

Associated Targets(Human)

PTPRC Tchem Receptor-type tyrosine-protein phosphatase C (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

CD45RA Mouse mAb (Ab006750) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD45RA with CD45RA Mouse mAb (Ab006750) conjugated with biotin (right panel) at 0.1 μg/mL for 1 hour at 4°C, compared with mouse IgG (Ab170221) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).

CD45RA Mouse mAb (Ab006750) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD45RA (red) with CD45RA Mouse mAb (Ab006750) conjugated with biotin at 0.1 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Isotype control, mouse IgG (Ab170221) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.

CD45RA Mouse mAb (Ab006750) - Flow Cytometry
Flow Cytometry analysis of Raji cells labelling CD45RA (red) with CD45RA Mouse mAb (Ab006750) at 0.1 μg/mL for 1 hour at 4°C. AffiniPure Goat anti-Mouse IgG, Fcγ fragment specific (AF647) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.

Application

Application Dilution info
Flow

< 0.5µg/100w cells

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F1201950 Certificate of Analysis Dec 06, 2023 Ab006750
ZJ23F1201951 Certificate of Analysis Dec 06, 2023 Ab006750

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