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CD18 Rat mAb - Primary antibody, specific to CD18, Rat IgG2a

COA COA
    Application:
  • Animal Model
  • Flow Cytometry
  • Functional Assay
  • Neutralization
  • Host species: Rat
  • Reactive species: Mouse
  • Isotype: Rat IgG2a
  • Clone Number: M18/2
  • Conjugation: Unconjugated
In stock
Item Number
Ab094077
Grouped product items
SKU Size
Availability
 Price Qty
Ab094077-10μg
10μg
10
$29.90
Ab094077-50μg
50μg
4
$69.90
Ab094077-100μg
100μg
2
$99.90
Ab094077-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$219.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

mAb (M18/2); Rat anti Mouse CD18 Antibody; in vivo LFA-1 neutralization, Flow; Unconjugated

View related series
Click to view target information: ITGB2
Accession#: P11835 (3) CD18 (6) Flow Cytometry (1158) Gene ID: 16414 (3) ITGB2 (4)

Basic Description

Product Name CD18 Rat mAb - Primary antibody, specific to CD18, Rat IgG2a
Synonyms 2E6 | Cd18 | Lfa1 | 959 beta subunit precursor)10 | CD18 antigen | CD18 | CD18beta 2 | cell surface adhesion glycoprotein (LFA-1 | CR3 | Integrin beta 2 | integrin beta-2 | integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1 | m
Specifications & Purity Carrier Free, Azide Free, Validated, ≥95%(SDS-PAGE), See COA
Host species Rat
Specificity CD18
Immunogen C57BL/10 splenocytes
Conjugation Unconjugated
Grade Azide Free, Carrier Free, Validated
Product Description

Rat anti Mouse CD18 Antibody, Monoclonal (M18/2), could be used for in vivo LFA-1 neutralization, Flow and so on.
Application
Flow: Use at an assay dependent concentration.
in vivo LFA-1 neutralization: Use at an assay dependent concentration.
Protein Function
Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1.

Product Properties

Isotype Rat IgG2a
Light Chain Type kappa
Purification Method Protein G purified
Shape Liquid
Concentration See COA
Storage Temp Store at 2-8°C,Do not freeze
Shipped In Wet ice
Stability And Storage Shipped at 4°C. Store at 4°C long term (12 months). Do not freeze. Upon receipt, it is recommended to aliquot.

Associated Targets(Human)

ITGB2 Tclin Integrin beta-2 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
ITGB2 Tclin Integrin beta-2 (0 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ITGB2 Tclin Integrin alpha-M/beta-2 (32 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

CD18 Rat mAb (Ab094077) - Flow Cytometry
Flow Cytometry analysis of mouse splenocytes cells labelling CD18 with CD18 Rat mAb (Ab094077) conjugated with biotin (right panel) at 0.5 μg/mL for 1 hour at 4°C, compared with Rat IgG Isotype Control Antibody (Biotin) (Ab180310) (left panel) and detected with SA-PE (rp156150).

CD18 Rat mAb (Ab094077) - Flow Cytometry
Flow Cytometry analysis of mouse splenocytes cells labelling CD18 (red) with CD18 Rat mAb (Ab094077) conjugated with biotin at 0.5 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Rat IgG Isotype Control Antibody (Biotin) (Ab180310). Black - Unlabelled control, cells without incubation with primary antibody.

Application

Application Dilution info
Flow Cytometry

Use at an assay dependent concentration.
in vivo LFA-1 neutralization

Use at an assay dependent concentration.

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0607305 Certificate of Analysis Mar 26, 2025 Ab094077
ZJ24F0607307 Certificate of Analysis Jun 25, 2024 Ab094077
ZJ24F0607306 Certificate of Analysis Jun 25, 2024 Ab094077

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