Search results for: '19463'

AS-604850, Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit gamma
Cas Number: 648449-76-7

Formula: C₁₁H₅F₂NO₄S

Molecular weight: 285.22

Synonyms: (E)-5-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)methylene)thiazolidine-2,4-dione | AS604850 | AS-604850...

SMILES: C1=CC2=C(C=C1C=C3C(=O)NC(=O)S3)OC(O2)(F)F

InChIKey: SRLVNYDXMUGOFI-XBXARRHUSA-N

InChI: InChI=1S/C11H5F2NO4S/c12-11(13)17-6-2-1-5(3-7(6)18-11)4-8-9(15)14-10(16)19-8/h1-4H,(H,14,15,16)/b8-4+
- Product No.
- Description
- Grade & Purity (?)
- A129517
  AS-604850, Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit gamma
  - ≥98%
  | Pricing Close
AS-605240, Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit beta;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit delta;Inhi
Cas Number: 648450-29-7

Formula: C₁₂H₇N₃O₂S

Molecular weight: 257.27

Synonyms: 5-(6-Quinoxalinylmethylene)-2,4-thiazolidine-2,4-dione | (5Z)-5-(quinoxalin-6-ylmethylidene)-1,3-thi...

SMILES: C1=CC2=NC=CN=C2C=C1C=C3C(=O)NC(=O)S3

InChIKey: SQWZFLMPDUSYGV-POHAHGRESA-N

InChI: InChI=1S/C12H7N3O2S/c16-11-10(18-12(17)15-11)6-7-1-2-8-9(5-7)14-4-3-13-8/h1-6H,(H,15,16,17)/b10-6-
- Product No.
- Description
- Grade & Purity (?)
- A127765
  AS-605240, Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit beta;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit delta;Inhi
  - ≥98%
  | Pricing Close
N-[6-[6-chloro-5-[(4-fluorophenyl)sulfonylamino]pyridin-3-yl]-1,3-benzothiazol-2-yl]acetamide, Inhibitor of mechanistic target of rapamycin kinase;Inhibitor of phosphatidylinositol 3-kinase catalytic subunit type 3;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate
Cas Number: 1112980-86-5

Synonyms: compound 82

SMILES: CC(=O)Nc1nc2c(s1)cc(cc2)c1cnc(c(c1)NS(=O)(=O)c1ccc(cc1)F)Cl

InChIKey: YGBMCLDVRUGXOV-UHFFFAOYSA-N

InChI: InChI=1S/C20H14ClFN4O3S2/c1-11(27)24-20-25-16-7-2-12(9-18(16)30-20)13-8-17(19(21)23-10-13)26-31(28,29)15-5-3-14(22)4-6-15/h2-10,26H,1H3,(H,24,25,27)
- Product No.
- Description
- Grade & Purity (?)
- N609439
  N-[6-[6-chloro-5-[(4-fluorophenyl)sulfonylamino]pyridin-3-yl]-1,3-benzothiazol-2-yl]acetamide, Inhibitor of mechanistic target of rapamycin kinase;Inhibitor of phosphatidylinositol 3-kinase catalytic subunit type 3;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate
  | Pricing Close
BGT-226, Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit beta;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit gamma
Cas Number: 915020-55-2

Formula: C₂₈H₂₅F₃N₆O₂

Molecular weight: 534.53

Synonyms: 8-(6-Methoxypyridin-3-yl)-3-methyl-1-(4-(piperazin-1-yl)-3-(trifluoromethyl)phenyl)-1,3-dihydro-2H-i...

SMILES: CN1C2=CN=C3C=CC(=CC3=C2N(C1=O)C4=CC(=C(C=C4)N5CCNCC5)C(F)(F)F)C6=CN=C(C=C6)OC

InChIKey: BMMXYEBLEBULND-UHFFFAOYSA-N

InChI: InChI=1S/C28H25F3N6O2/c1-35-24-16-33-22-6-3-17(18-4-8-25(39-2)34-15-18)13-20(22)26(24)37(27(35)38)19-5-7-23(21(14-19)28(29,30)31)36-11-9-32-10-12-36/h3-8,13-16,32H,9-12H2,1-2H3
- Product No.
- Description
- Grade & Purity (?)
- B608036
  BGT-226, Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit beta;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit gamma
  | Pricing Close
AZD8154, Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit beta;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit delta;Inhi
Synonyms: AZD8154 | AZD-8154 | 2-[(1S)-1-cyclopropylethyl]-5-[4-methyl-2-[[6-(2-oxopyrrolidin-1-yl)pyridin-2-y...

SMILES: C[C@H](N1Cc2c(C1=O)c(cc(c2)c1sc(nc1C)Nc1cccc(n1)N1CCCC1=O)S(=O)(=O)C)C1CC1

InChIKey: XOMFDZJQLSPGGV-INIZCTEOSA-N

InChI: InChI=1S/C27H29N5O4S2/c1-15-25(37-27(28-15)30-21-6-4-7-22(29-21)31-11-5-8-23(31)33)18-12-19-14-32(16(2)17-9-10-17)26(34)24(19)20(13-18)38(3,35)36/h4,6-7,12-13,16-17H,5,8-11,14H2,1-3H3,(H,28,29,30)/t16See more
- Product No.
- Description
- Grade & Purity (?)
- A607886
  AZD8154, Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit beta;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit delta;Inhi
  | Pricing Close
GDC-0077, Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit beta;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit delta;Inhi
Cas Number: 2060571-02-8

Formula: C₁₈H₁₉F₂N₅O₄

Molecular weight: 407.37

Synonyms: (S)-2-((2-((S)-4-(difluoromethyl)-2-oxooxazolidin-3-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazep...

SMILES: CC(C(=O)N)NC1=CC2=C(C=C1)C3=NC(=CN3CCO2)N4C(COC4=O)C(F)F

InChIKey: SGEUNORSOZVTOL-CABZTGNLSA-N

InChI: InChI=1S/C18H19F2N5O4/c1-9(16(21)26)22-10-2-3-11-13(6-10)28-5-4-24-7-14(23-17(11)24)25-12(15(19)20)8-29-18(25)27/h2-3,6-7,9,12,15,22H,4-5,8H2,1H3,(H2,21,26)/t9-,12-/m0/s1
- Product No.
- Description
- Grade & Purity (?)
- G419993
  GDC-0077, Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit beta;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit delta;Inhi
  - ≥98%
  | Pricing Close
AZD7648, Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit gamma;Inhibitor of protein kinase; DNA-activated; catalytic subunit
Cas Number: 2230820-11-6

Formula: C₁₈H₂₀N₈O₂

Molecular weight: 380.4

Synonyms: 7-methyl-2-[(7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino]-9-(oxan-4-yl)purin-8-one | SB23233 |...

SMILES: CC1=CC2=NC=NN2C=C1NC3=NC=C4C(=N3)N(C(=O)N4C)C5CCOCC5

InChIKey: XISVSTPEXYIKJL-UHFFFAOYSA-N

InChI: InChI=1S/C18H20N8O2/c1-11-7-15-20-10-21-25(15)9-13(11)22-17-19-8-14-16(23-17)26(18(27)24(14)2)12-3-5-28-6-4-12/h7-10,12H,3-6H2,1-2H3,(H,19,22,23)
- Product No.
- Description
- Grade & Purity (?)
- A414215
  AZD7648, Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit gamma;Inhibitor of protein kinase; DNA-activated; catalytic subunit
  - ≥98%
  | Pricing Close
XL147, Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit beta;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit delta;Inhi
Cas Number: 956958-53-5

Formula: C₂₁H₁₆N₆O₂S₂

Molecular weight: 448.52

Synonyms: XL 147 | AKOS022131419 | MFCD16621245 | BCP01861 | N-[3-(2,1,3-Benzothiadiazol-5-ylamino)-2-quinoxal...

SMILES: CC1=CC=C(C=C1)S(=O)(=O)NC2=NC3=CC=CC=C3N=C2NC4=CC5=NSN=C5C=C4

InChIKey: MQMKRQLTIWPEDM-UHFFFAOYSA-N

InChI: InChI=1S/C21H16N6O2S2/c1-13-6-9-15(10-7-13)31(28,29)27-21-20(23-16-4-2-3-5-17(16)24-21)22-14-8-11-18-19(12-14)26-30-25-18/h2-12H,1H3,(H,22,23)(H,24,27)
- Product No.
- Description
- Grade & Purity (?)
- X129499
  XL147, Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit beta;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit delta;Inhi
  - ≥98%
  | Pricing Close
Zandelisib, PI3-kinase p110-delta subunit inhibitor
Cas Number: 1401436-95-0

Formula: C₃₁H₃₈F₂N₈O

Molecular weight: 576.7

Synonyms: ZANDELISIB [JAN] | MS-30369 | Zandelisib [INN] | 8Z28M5SX0X | Zandelisib [USAN] | Zandelisib | 1,3,5...

SMILES: CC(C)(CC1=CC=CC=C1C2CCN(CC2)C)NC3=NC(=NC(=N3)N4CCOCC4)N5C6=CC=CC=C6N=C5C(F)F

InChIKey: WPFUFWIHMYZXSF-UHFFFAOYSA-N

InChI: InChI=1S/C31H38F2N8O/c1-31(2,20-22-8-4-5-9-23(22)21-12-14-39(3)15-13-21)38-28-35-29(40-16-18-42-19-17-40)37-30(36-28)41-25-11-7-6-10-24(25)34-27(41)26(32)33/h4-11,21,26H,12-20H2,1-3H3,(H,35,36,37,38)
- Product No.
- Description
- Grade & Purity (?)
- Z413033
  Zandelisib, PI3-kinase p110-delta subunit inhibitor
  - ≥98%
  | Pricing Close
CAL-101, PI3-kinase p110-delta subunit inhibitor
2 Citations

Cas Number: 870281-82-6

Formula: C₂₂H₁₈FN₇O

Molecular weight: 415.43

Synonyms: AMY9239 | GS-11CAL-101 | IC489666 | 5-fluoro-3-phenyl-2-((1s)-1-(9h-purin-6-ylamino)propyl)-4(3h)-qu...

SMILES: CCC(C1=NC2=C(C(=CC=C2)F)C(=O)N1C3=CC=CC=C3)NC4=NC=NC5=C4NC=N5

InChIKey: IFSDAJWBUCMOAH-HNNXBMFYSA-N

InChI: InChI=1S/C22H18FN7O/c1-2-15(28-20-18-19(25-11-24-18)26-12-27-20)21-29-16-10-6-9-14(23)17(16)22(31)30(21)13-7-4-3-5-8-13/h3-12,15H,2H2,1H3,(H2,24,25,26,27,28)/t15-/m0/s1
- Product No.
- Description
- Grade & Purity (?)
- C127044
  CAL-101, PI3-kinase p110-delta subunit inhibitor
  - ≥99%
  | Pricing Close
LY 294002 (DMSO solution), Inhibitor of bromodomain containing 2;Inhibitor of bromodomain containing 3;Inhibitor of bromodomain containing 4;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kina
11 Citations

Cas Number: 154447-36-6

Formula: C₁₉H₁₇NO₃

Molecular weight: 307.35

Synonyms: SCHEMBL94377 | 31M2U1DVID | J-510126 | NCGC00015622-07 | s1105 | BiomolKI_000029 | DTXSID6042650 | E...

SMILES: C1COCCN1C2=CC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC=C4

InChIKey: CZQHHVNHHHRRDU-UHFFFAOYSA-N

InChI: InChI=1S/C19H17NO3/c21-17-13-18(20-9-11-22-12-10-20)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14/h1-8,13H,9-12H2
- Product No.
- Description
- Grade & Purity (?)
- L276596
  LY 294002 (DMSO solution), Inhibitor of bromodomain containing 2;Inhibitor of bromodomain containing 3;Inhibitor of bromodomain containing 4;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kina
  - ≥98%
  - 10mM in DMSO
  | Pricing Close
STK16-IN-1, Inhibitor of mechanistic target of rapamycin kinase;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit delta;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit gamma;Inhibitor of serine/threonine kinas
Cas Number: 1223001-53-3

Formula: C₁₇H₁₂FN₃O

Molecular weight: 293.3

Synonyms: SCHEMBL1368254 | 1-(4-fluoro-3-methylphenyl)-1H-pyrrolo[2,3-h][1,6]naphthyridin-2(7H)-one | YYB00153...

SMILES: CC1=C(C=CC(=C1)N2C(=O)C=CC3=CN=C4C(=C32)C=CN4)F

InChIKey: WQNRDXHKVSKUPI-UHFFFAOYSA-N

InChI: InChI=1S/C17H12FN3O/c1-10-8-12(3-4-14(10)18)21-15(22)5-2-11-9-20-17-13(16(11)21)6-7-19-17/h2-9H,1H3,(H,19,20)
- Product No.
- Description
- Grade & Purity (?)
- S287393
  STK16-IN-1, Inhibitor of mechanistic target of rapamycin kinase;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit delta;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit gamma;Inhibitor of serine/threonine kinas
  - ≥98%(HPLC)
  | Pricing Close
azd-8186, PI3-kinase p110-delta subunit inhibitor
Cas Number: 1627494-13-6

Formula: C₂₄H₂₅F₂N₃O₄

Molecular weight: 457.478

Synonyms: 8-[(1R)-1-[(3,5-difluorophenyl)amino]ethyl]-N,N-dimethyl-2-(morpholin-4-yl)-4-oxo-4H-chromene-6-carb...

SMILES: CC(C1=CC(=CC2=C1OC(=CC2=O)N3CCOCC3)C(=O)N(C)C)NC4=CC(=CC(=C4)F)F

InChIKey: LMJFJIDLEAWOQJ-CQSZACIVSA-N

InChI: InChI=1S/C24H25F2N3O4/c1-14(27-18-11-16(25)10-17(26)12-18)19-8-15(24(31)28(2)3)9-20-21(30)13-22(33-23(19)20)29-4-6-32-7-5-29/h8-14,27H,4-7H2,1-3H3/t14-/m1/s1
- Product No.
- Description
- Grade & Purity (?)
- A174656
  azd-8186, PI3-kinase p110-delta subunit inhibitor
  - ≥98%
  | Pricing Close
(R)-2-Methoxy-N-(2-methoxy-5-(7-((4-(oxetan-3-yl)morpholin-2-yl)methoxy)-1,3-dihydroisobenzofuran-5-yl)pyridin-3-yl)ethanesulfonamide, Inhibitor of phosphatidylinositol 3-kinase catalytic subunit type 3;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit beta;Inhibitor of phospha
Synonyms: compound 41

SMILES: COCCS(=O)(=O)Nc1cc(cnc1OC)c1cc(OC[C@@H]2OCCN(C2)C2COC2)c2c(c1)COC2

InChIKey: ZWPJBXLFZFLGMV-OAQYLSRUSA-N

InChI: InChI=1S/C25H33N3O8S/c1-31-5-6-37(29,30)27-23-8-18(10-26-25(23)32-2)17-7-19-12-33-16-22(19)24(9-17)36-15-21-11-28(3-4-35-21)20-13-34-14-20/h7-10,20-21,27H,3-6,11-16H2,1-2H3/t21-/m1/s1
- Product No.
- Description
- Grade & Purity (?)
- R609220
  (R)-2-Methoxy-N-(2-methoxy-5-(7-((4-(oxetan-3-yl)morpholin-2-yl)methoxy)-1,3-dihydroisobenzofuran-5-yl)pyridin-3-yl)ethanesulfonamide, Inhibitor of phosphatidylinositol 3-kinase catalytic subunit type 3;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit beta;Inhibitor of phospha
  | Pricing Close
CH5132799, PI3-kinase class I inhibitor
Cas Number: 1007207-67-1

Formula: C₁₅H₁₉N₇O₃S

Molecular weight: 377.42

Synonyms: UNII-JCL936W835 | AC-28422 | 5-(7-methylsulfonyl-2-morpholin-4-yl-5,6-dihydropyrrolo[2,3-d]pyrimidin...

SMILES: CS(=O)(=O)N1CCC2=C(N=C(N=C21)N3CCOCC3)C4=CN=C(N=C4)N

InChIKey: JEGHXKRHKHPBJD-UHFFFAOYSA-N

InChI: InChI=1S/C15H19N7O3S/c1-26(23,24)22-3-2-11-12(10-8-17-14(16)18-9-10)19-15(20-13(11)22)21-4-6-25-7-5-21/h8-9H,2-7H2,1H3,(H2,16,17,18)
- Product No.
- Description
- Grade & Purity (?)
- C127596
  CH5132799, PI3-kinase class I inhibitor
  - ≥97%
  | Pricing Close
ZSTK474, PI3-kinase class I inhibitor
Cas Number: 475110-96-4

Formula: C₁₉H₂₁F₂N₇O₂

Molecular weight: 417.42

Synonyms: BRD-K63068307-001-01-4 | TCMDC-137004 | 4,4''-(6-(2-(difluoromethyl)-1H-benzo[d]imidazol-1-yl)-1,3,5...

SMILES: C1COCCN1C2=NC(=NC(=N2)N3C4=CC=CC=C4N=C3C(F)F)N5CCOCC5

InChIKey: HGVNLRPZOWWDKD-UHFFFAOYSA-N

InChI: InChI=1S/C19H21F2N7O2/c20-15(21)16-22-13-3-1-2-4-14(13)28(16)19-24-17(26-5-9-29-10-6-26)23-18(25-19)27-7-11-30-12-8-27/h1-4,15H,5-12H2
- Product No.
- Description
- Grade & Purity (?)
- Z126804
  ZSTK474, PI3-kinase class I inhibitor
  - ≥98%
  | Pricing Close
acalisib (GS-9820), PI3-kinase p110-delta subunit inhibitor
Cas Number: 870281-34-8

Formula: C₂₁H₁₆FN₇O

Molecular weight: 401.4

Synonyms: 5-amino-3-tert-butyl-n-p-tolylpyrazole | HY-12644 | NCGC00229746-04 | (S)-2-(1-(9H-Purin-6-ylamino)e...

SMILES: CC(C1=NC2=C(C=C(C=C2)F)C(=O)N1C3=CC=CC=C3)NC4=NC=NC5=C4NC=N5

InChIKey: DOCINCLJNAXZQF-LBPRGKRZSA-N

InChI: InChI=1S/C21H16FN7O/c1-12(27-19-17-18(24-10-23-17)25-11-26-19)20-28-16-8-7-13(22)9-15(16)21(30)29(20)14-5-3-2-4-6-14/h2-12H,1H3,(H2,23,24,25,26,27)/t12-/m0/s1
- Product No.
- Description
- Grade & Purity (?)
- A413341
  acalisib (GS-9820), PI3-kinase p110-delta subunit inhibitor
  - ≥99%
  | Pricing Close
GDC-0941, PI3-kinase class I inhibitor
Cas Number: 957054-30-7

Formula: C₂₃H₂₇N₇O₃S₂

Molecular weight: 513.64

Synonyms: s7808 | TXCWBWKVIZGWEQ-UHFFFAOYSA-N | HMS3244H10 | HMS3265J06 | Pictilisib [USAN:INN] | s1065 | Pict...

SMILES: CS(=O)(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6

InChIKey: LHNIIDJUOCFXAP-UHFFFAOYSA-N

InChI: InChI=1S/C23H27N7O3S2/c1-35(31,32)30-7-5-28(6-8-30)15-16-13-20-21(34-16)23(29-9-11-33-12-10-29)26-22(25-20)17-3-2-4-19-18(17)14-24-27-19/h2-4,13-14H,5-12,15H2,1H3,(H,24,27)
- Product No.
- Description
- Grade & Purity (?)
- G126357
  GDC-0941, PI3-kinase class I inhibitor
  - ≥98%
  | Pricing Close
2,4-Difluoro-N-(2-methoxy-5-(3-(5-(2-(4-methylpiperazin-1-yl)ethyl)-1,3,4-oxadiazol-2-yl)imidazo[1,2-a]pyridin-6-yl)pyridin-3-yl)benzenesulfonamide, Inhibitor of mechanistic target of rapamycin kinase;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit beta;Inhibitor of phosphatidylinositol-4;
Synonyms: compound 15a

SMILES: COc1ncc(cc1NS(=O)(=O)c1ccc(cc1F)F)c1ccc2n(c1)c(cn2)c1nnc(o1)CCN1CCN(CC1)C

InChIKey: LSPJWTULWKYRTQ-UHFFFAOYSA-N

InChI: InChI=1S/C28H28F2N8O4S/c1-36-9-11-37(12-10-36)8-7-26-33-34-28(42-26)23-16-31-25-6-3-18(17-38(23)25)19-13-22(27(41-2)32-15-19)35-43(39,40)24-5-4-20(29)14-21(24)30/h3-6,13-17,35H,7-12H2,1-2H3
- Product No.
- Description
- Grade & Purity (?)
- D608737
  2,4-Difluoro-N-(2-methoxy-5-(3-(5-(2-(4-methylpiperazin-1-yl)ethyl)-1,3,4-oxadiazol-2-yl)imidazo[1,2-a]pyridin-6-yl)pyridin-3-yl)benzenesulfonamide, Inhibitor of mechanistic target of rapamycin kinase;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit beta;Inhibitor of phosphatidylinositol-4;
  | Pricing Close
TG100-115, PI3-kinase p110-delta subunit inhibitor
Cas Number: 677297-51-7

Formula: C₁₈H₁₄N₆O₂

Molecular weight: 346.35

Synonyms: adenosine-5'-diphosphate monothiophosphate | 6,7-bis(3-hydroxyphenyl)-pteridine-2,4-diamine | 6,7-Bi...

SMILES: C1=CC(=CC(=C1)O)C2=NC3=C(N=C(N=C3N=C2C4=CC(=CC=C4)O)N)N

InChIKey: UJIAQDJKSXQLIT-UHFFFAOYSA-N

InChI: InChI=1S/C18H14N6O2/c19-16-15-17(24-18(20)23-16)22-14(10-4-2-6-12(26)8-10)13(21-15)9-3-1-5-11(25)7-9/h1-8,25-26H,(H4,19,20,22,23,24)
- Product No.
- Description
- Grade & Purity (?)
- T127783
  TG100-115, PI3-kinase p110-delta subunit inhibitor
  - ≥98%
  | Pricing Close
Serabelisib, PI3-kinase p110-alpha subunit inhibitor
Cas Number: 1268454-23-4

Formula: C₁₉H₁₇N₅O₃

Molecular weight: 363.37

Synonyms: MLN1117 (INK1117) | (6-(2-amino-1,3-benzoxazol-5-yl)imidazo(1,2-a)pyridin-3-yl)(4-morpholinyl)methan...

SMILES: C1COCCN1C(=O)C2=CN=C3N2C=C(C=C3)C4=CC5=C(C=C4)OC(=N5)N

InChIKey: BLGWHBSBBJNKJO-UHFFFAOYSA-N

InChI: InChI=1S/C19H17N5O3/c20-19-22-14-9-12(1-3-16(14)27-19)13-2-4-17-21-10-15(24(17)11-13)18(25)23-5-7-26-8-6-23/h1-4,9-11H,5-8H2,(H2,20,22)
- Product No.
- Description
- Grade & Purity (?)
- S276459
  Serabelisib, PI3-kinase p110-alpha subunit inhibitor
  - ≥98%
  | Pricing Close
Berzosertib, Serine-protein kinase ATR inhibitor
Cas Number: 1232416-25-9

Formula: C₂₄H₂₅N₅O₃S

Molecular weight: 463.55

Synonyms: 5-(4-(isopropylsulfonyl)phenyl)-3-(3-(4-((methylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amine | ...

SMILES: CC(C)S(=O)(=O)C1=CC=C(C=C1)C2=CN=C(C(=N2)C3=CC(=NO3)C4=CC=C(C=C4)CNC)N

InChIKey: JZCWLJDSIRUGIN-UHFFFAOYSA-N

InChI: InChI=1S/C24H25N5O3S/c1-15(2)33(30,31)19-10-8-18(9-11-19)21-14-27-24(25)23(28-21)22-12-20(29-32-22)17-6-4-16(5-7-17)13-26-3/h4-12,14-15,26H,13H2,1-3H3,(H2,25,27)
- Product No.
- Description
- Grade & Purity (?)
- V275936
  Berzosertib, Serine-protein kinase ATR inhibitor
  - ≥98%
  | Pricing Close
AMG319, Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit beta;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit delta;Inhi
Cas Number: 1608125-21-8

Formula: C₂₁H₁₆FN₇

Molecular weight: 385.4

Synonyms: AMG319 | AMG-319 | (S)-N-(1-(7-fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine | 160812...

SMILES: CC(C1=C(N=C2C=C(C=CC2=C1)F)C3=CC=CC=N3)NC4=NC=NC5=C4NC=N5

InChIKey: KWRYMZHCQIOOEB-LBPRGKRZSA-N

InChI: InChI=1S/C21H16FN7/c1-12(28-21-19-20(25-10-24-19)26-11-27-21)15-8-13-5-6-14(22)9-17(13)29-18(15)16-4-2-3-7-23-16/h2-12H,1H3,(H2,24,25,26,27,28)/t12-/m0/s1
- Product No.
- Description
- Grade & Purity (?)
- A413839
  AMG319, Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit beta;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit delta;Inhi
  - ≥99%
  | Pricing Close
AS-252424, Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit gamma
Cas Number: 900515-16-4

Formula: C₁₄H₈FNO₄S

Molecular weight: 305.28

Synonyms: HMS3229L07 | SCHEMBL1494573 | 2,4-Thiazolidinedione, 5-((5-(4-fluoro-2-hydroxyphenyl)-2-furanyl)meth...

SMILES: C1=CC(=C(C=C1F)O)C2=CC=C(O2)C=C3C(=O)NC(=O)S3

InChIKey: OYYVWNDMOQPMGE-SDQBBNPISA-N

InChI: InChI=1S/C14H8FNO4S/c15-7-1-3-9(10(17)5-7)11-4-2-8(20-11)6-12-13(18)16-14(19)21-12/h1-6,17H,(H,16,18,19)/b12-6-
- Product No.
- Description
- Grade & Purity (?)
- A129503
  AS-252424, Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit alpha;Inhibitor of phosphatidylinositol-4;5-bisphosphate 3-kinase catalytic subunit gamma
  - ≥98%
  | Pricing Close