sp_3336_rock-Aladdin Scientific

, Inhibitor of Rho associated coiled-coil containing protein kinase 1;Inhibitor of Rho associated coiled-coil containing protein kinase 2

Wish List Compare

GSK 269962, Inhibitor of Rho associated coiled-coil containing protein kinase 1;Inhibitor of Rho associated coiled-coil containing protein kinase 2

Grade & Purity:

Moligand™

10mM in DMSO

Cas Number: 850664-21-0

Formula: C₂₉H₃₀N₈O₅ Molecular Weight: 570.6

IUPAC Name: N-[3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethylimidazo[4,5-c]pyridin-6-yl]oxyphenyl]-4-(2-morpholin-4-ylethoxy)benzamide

SMILES: CCN1C2=CC(=NC=C2N=C1C3=NON=C3N)OC4=CC=CC(=C4)NC(=O)C5=CC=C(C=C5)OCCN6CCOCC6

InChIKey: YOVNFNXUCOWYSG-UHFFFAOYSA-N

InChI: InChI=1S/C29H30N8O5/c1-2-37-24-17-25(31-18-23(24)33-28(37)26-27(30)35-42-34-26)41-22-5-3-4-20(16-22)32-29(38)19-6-8-21(9-7-19)40-15-12-36-10-13-39-14-show more

Synonyms: GSK269962A|850664-21-0|GSK 269962|GSK-269962A|925213-63-4|GSK269962|GSK 269962A|N-[3-[2-(4-amino-1,2,5-oxadiazol-3-yl...

Details

Pricing Close

Wish List Compare

GSK180736A (GSK180736)

Grade & Purity:

10mM in DMSO

Cas Number: 817194-38-0

Formula: C₁₉H₁₆FN₅O₂ Molecular Weight: 365.36

IUPAC Name: 4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxamide

SMILES: CC1=C(C(NC(=O)N1)C2=CC=C(C=C2)F)C(=O)NC3=CC4=C(C=C3)NN=C4

InChIKey: HEAIGWIZTYAQTC-UHFFFAOYSA-N

InChI: InChI=1S/C19H16FN5O2/c1-10-16(17(24-19(27)22-10)11-2-4-13(20)5-3-11)18(26)23-14-6-7-15-12(8-14)9-21-25-15/h2-9,17H,1H3,(H,21,25)(H,23,26)(H2,22,24,27)

Synonyms: 5-Pyrimidinecarboxamide,4-(4-fluorophenyl)-1,2,3,4-tetrahydro-N-1H-indazol-5-yl-6-methyl-2-oxo-

Details

Pricing Close

Wish List Compare

GSK180736A (GSK180736)

Grade & Purity:

≥98%

Cas Number: 817194-38-0

Formula: C₁₉H₁₆FN₅O₂ Molecular Weight: 365.36

IUPAC Name: 4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxamide

SMILES: CC1=C(C(NC(=O)N1)C2=CC=C(C=C2)F)C(=O)NC3=CC4=C(C=C3)NN=C4

InChIKey: HEAIGWIZTYAQTC-UHFFFAOYSA-N

InChI: InChI=1S/C19H16FN5O2/c1-10-16(17(24-19(27)22-10)11-2-4-13(20)5-3-11)18(26)23-14-6-7-15-12(8-14)9-21-25-15/h2-9,17H,1H3,(H,21,25)(H,23,26)(H2,22,24,27)

Synonyms: 5-Pyrimidinecarboxamide,4-(4-fluorophenyl)-1,2,3,4-tetrahydro-N-1H-indazol-5-yl-6-methyl-2-oxo-修改下顺序...

Details

Pricing Close

Wish List Compare

GSK269962A HCl

Grade & Purity:

≥98%

Cas Number: 2095432-71-4

Formula: C₂₉H₃₀N₈O₅.HCl Molecular Weight: 607.06

IUPAC Name: N-[3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethylimidazo[4,5-c]pyridin-6-yl]oxyphenyl]-4-(2-morpholin-4-ylethoxy)benzamide;hydrochloride

SMILES: CCN1C2=CC(=NC=C2N=C1C3=NON=C3N)OC4=CC=CC(=C4)NC(=O)C5=CC=C(C=C5)OCCN6CCOCC6.Cl

InChIKey: UYKVMFKKKLLDGL-UHFFFAOYSA-N

InChI: InChI=1S/C29H30N8O5.ClH/c1-2-37-24-17-25(31-18-23(24)33-28(37)26-27(30)35-42-34-26)41-22-5-3-4-20(16-22)32-29(38)19-6-8-21(9-7-19)40-15-12-36-10-13-39show more

Synonyms: GSK269962B | GSK269962 | GSK 269962Benzamide,N-[3-[[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidaz...

Details

Pricing Close

Wish List Compare

GSK429286A (DMSO solution)

Grade & Purity:

Moligand™

≥98%

Cas Number: 864082-47-3

Formula: C₂₁H₁₆F₄N₄O₂ Molecular Weight: 432.37

IUPAC Name: N-(6-fluoro-1H-indazol-5-yl)-6-methyl-2-oxo-4-[4-(trifluoromethyl)phenyl]-3,4-dihydro-1H-pyridine-5-carboxamide

SMILES: CC1=C(C(CC(=O)N1)C2=CC=C(C=C2)C(F)(F)F)C(=O)NC3=C(C=C4C(=C3)C=NN4)F

InChIKey: OLIIUAHHAZEXEX-UHFFFAOYSA-N

InChI: InChI=1S/C21H16F4N4O2/c1-10-19(20(31)28-17-6-12-9-26-29-16(12)8-15(17)22)14(7-18(30)27-10)11-2-4-13(5-3-11)21(23,24)25/h2-6,8-9,14H,7H2,1H3,(H,26,29)(show more

Details

Pricing Close

Wish List Compare

Glycyl-H 1152 dihydrochloride

Grade & Purity:

≥99%(HPLC)

Cas Number: 913844-45-8 Compound CID: 56972177

Formula: C₁₈H₂₄N₄O₃S•2HCl Molecular Weight: 449.4

IUPAC Name: 2-amino-1-[(3S)-3-methyl-4-(4-methylisoquinolin-5-yl)sulfonyl-1,4-diazepan-1-yl]ethanone;dihydrochloride

SMILES: CC1CN(CCCN1S(=O)(=O)C2=CC=CC3=C2C(=CN=C3)C)C(=O)CN.Cl.Cl

InChIKey: ILDBNQGLZFSHQZ-UTLKBRERSA-N

InChI: InChI=1S/C18H24N4O3S.2ClH/c1-13-10-20-11-15-5-3-6-16(18(13)15)26(24,25)22-8-4-7-21(12-14(22)2)17(23)9-19;;/h3,5-6,10-11,14H,4,7-9,12,19H2,1-2H3;2*1H/tshow more

Synonyms: (S)-(+)-4-Glycyl-2-methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-hexahydro-1H-1,4-diazepine dihydrochloride

Details

Pricing Close

Wish List Compare

H 1152 dihydrochloride

Grade & Purity:

10mM in DMSO

Cas Number: 871543-07-6 Compound CID: 11560225

Formula: C₁₆H₂₃Cl₂N₃O₂S Molecular Weight: 392.34

IUPAC Name: 4-methyl-5-[[(2S)-2-methyl-1,4-diazepan-1-yl]sulfonyl]isoquinoline;dihydrochloride

SMILES: CC1CNCCCN1S(=O)(=O)C2=CC=CC3=C2C(=CN=C3)C.Cl.Cl

InChIKey: BFOPDSJOLUQULZ-GXKRWWSZSA-N

InChI: InChI=1S/C16H21N3O2S.2ClH/c1-12-9-18-11-14-5-3-6-15(16(12)14)22(20,21)19-8-4-7-17-10-13(19)2;;/h3,5-6,9,11,13,17H,4,7-8,10H2,1-2H3;2*1H/t13-;;/m0../s1

Synonyms: H-1152 Dihydrochloride|871543-07-6|H-1152 (dihydrochloride)|451462-58-1|H1152|4-methyl-5-[[(2S)-2-methyl-1,4-diazepan...

Details

Pricing Close

Wish List Compare

HA 1100 hydrochloride (Hydroxyfasudil)

Grade & Purity:

≥98%

Cas Number: 155558-32-0

Formula: C₁₄H₁₈ClN₃O₃S Molecular Weight: 343.83

IUPAC Name: 5-(1,4-diazepan-1-ylsulfonyl)-2H-isoquinolin-1-one;hydrochloride

SMILES: C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CNC3=O.Cl

InChIKey: XWWFOUVDVJGNNG-UHFFFAOYSA-N

InChI: InChI=1S/C14H17N3O3S.ClH/c18-14-12-3-1-4-13(11(12)5-7-16-14)21(19,20)17-9-2-6-15-8-10-17;/h1,3-5,7,15H,2,6,8-10H2,(H,16,18);1H

Synonyms: 155558-32-0 (HCl salt) | FD5036 | H1745 | HA 1100 hydrochloride | SR-00000002171 | 5-((1,4-diazepan-1-yl)sulfonyl)iso...

Details

Pricing Close

Wish List Compare

HA 1100 hydrochloride (Hydroxyfasudil)

Grade & Purity:

10mM in DMSO

Cas Number: 155558-32-0

Formula: C₁₄H₁₈ClN₃O₃S Molecular Weight: 343.83

IUPAC Name: 5-(1,4-diazepan-1-ylsulfonyl)-2H-isoquinolin-1-one;hydrochloride

SMILES: C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CNC3=O.Cl

InChIKey: XWWFOUVDVJGNNG-UHFFFAOYSA-N

InChI: InChI=1S/C14H17N3O3S.ClH/c18-14-12-3-1-4-13(11(12)5-7-16-14)21(19,20)17-9-2-6-15-8-10-17;/h1,3-5,7,15H,2,6,8-10H2,(H,16,18);1H

Details

Pricing Close

Wish List Compare

HA-100 dihydrochloride

Grade & Purity:

≥98%

Cas Number: 210297-47-5 Compound CID: 13135529

Formula: C₁₃H₁₅N₃O₂S • 2HCl Molecular Weight: 350.3

IUPAC Name: 5-piperazin-1-ylsulfonylisoquinoline;dihydrochloride

SMILES: C1CN(CCN1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3.Cl.Cl

InChIKey: ZKQAPKKKTQCVKG-UHFFFAOYSA-N

InChI: InChI=1S/C13H15N3O2S.2ClH/c17-19(18,16-8-6-14-7-9-16)13-3-1-2-11-10-15-5-4-12(11)13;;/h1-5,10,14H,6-9H2;2*1H

Synonyms: Isoquinoline,5-(1-piperazinylsulfonyl)-,hydrochloride (1:2) | 5-(1-piperazinylsulfonyl)-isoquinoline,dihydrochloride

Details

Pricing Close

Wish List Compare

HA-100 dihydrochloride

Grade & Purity:

10mM in DMSO

Cas Number: 210297-47-5 Compound CID: 13135529

Formula: C₁₃H₁₅N₃O₂S • 2HCl Molecular Weight: 350.3

IUPAC Name: 5-piperazin-1-ylsulfonylisoquinoline;dihydrochloride

SMILES: C1CN(CCN1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3.Cl.Cl

InChIKey: ZKQAPKKKTQCVKG-UHFFFAOYSA-N

InChI: InChI=1S/C13H15N3O2S.2ClH/c17-19(18,16-8-6-14-7-9-16)13-3-1-2-11-10-15-5-4-12(11)13;;/h1-5,10,14H,6-9H2;2*1H

Synonyms: Isoquinoline,5-(1-piperazinylsulfonyl)-,hydrochloride (1:2)

Details

Pricing Close

Wish List Compare

KD025 (SLx-2119), Inhibitor of Rho associated coiled-coil containing protein kinase 1;Inhibitor of Rho associated coiled-coil containing protein kinase 2

Grade & Purity:

Moligand™

10mM in DMSO

Cas Number: 911417-87-3

Formula: C₂₆H₂₄N₆O₂ Molecular Weight: 452.51

IUPAC Name: 2-[3-[4-(1H-indazol-5-ylamino)quinazolin-2-yl]phenoxy]-N-propan-2-ylacetamide

SMILES: CC(C)NC(=O)COC1=CC=CC(=C1)C2=NC3=CC=CC=C3C(=N2)NC4=CC5=C(C=C4)NN=C5

InChIKey: GKHIVNAUVKXIIY-UHFFFAOYSA-N

InChI: InChI=1S/C26H24N6O2/c1-16(2)28-24(33)15-34-20-7-5-6-17(13-20)25-30-23-9-4-3-8-21(23)26(31-25)29-19-10-11-22-18(12-19)14-27-32-22/h3-14,16H,15H2,1-2H3,show more

Synonyms: 911417-87-3|Belumosudil|SLx-2119|KD-025|KD025|2-(3-(4-((1H-indazol-5-yl)amino)quinazolin-2-yl)phenoxy)-N-isopropylace...

Details

Pricing Close

ROCK