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PD-1/PD-L1

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  1. PD-1/PD-L1-IN-10
      Grade & Purity: 
    • ≥99%
    Cas Number: 2487550-41-2        Compound CID:  156599565
    Formula:  C33H31N3O7        Molecular Weight: 581.62
    IUPAC Name:  (2S)-2-[[2-[(3-cyanophenyl)methoxy]-4-[(2-methyl-3-phenylphenyl)methoxy]-5-nitrophenyl]methylamino]-3-hydroxybutanoic acid
    SMILES:  CC1=C(C=CC=C1C2=CC=CC=C2)COC3=C(C=C(C(=C3)OCC4=CC(=CC=C4)C#N)CNC(C(C)O)C(=O)O)[N+](=O)[O-]
    InChIKey: KDEQMCUCWNLUJE-LKYSYNKGSA-N
    InChI:  InChI=1S/C33H31N3O7/c1-21-26(12-7-13-28(21)25-10-4-3-5-11-25)20-43-31-16-30(42-19-24-9-6-8-23(14-24)17-34)27(15-29(31)36(40)41)18-35-32(22(2)37)33(38)show more
  2. BMS-1166 hydrochloride
      Grade & Purity: 
    • ≥99%
    Cas Number: 2113650-05-6        Compound CID:  139035005
    Formula:  C36H34Cl2N2O7        Molecular Weight: 677.57
    IUPAC Name:  (2R,4R)-1-[[5-chloro-2-[(3-cyanophenyl)methoxy]-4-[[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylphenyl]methoxy]phenyl]methyl]-4-hydroxypyrrolidine-2-show more
    SMILES:  CC1=C(C=CC=C1C2=CC3=C(C=C2)OCCO3)COC4=C(C=C(C(=C4)OCC5=CC(=CC=C5)C#N)CN6CC(CC6C(=O)O)O)Cl.Cl
    InChIKey: HYWQPFPFYSOTHD-UVFMYQNSSA-N
    InChI:  InChI=1S/C36H33ClN2O7.ClH/c1-22-26(6-3-7-29(22)25-8-9-32-35(14-25)44-11-10-43-32)21-46-34-16-33(45-20-24-5-2-4-23(12-24)17-38)27(13-30(34)37)18-39-19-show more
  3. BMS-8
      Grade & Purity: 
    • ≥98%
    Cas Number: 1675201-90-7        Compound CID:  117941742
    Formula:  C27H28BrNO3        Molecular Weight: 494.42
    IUPAC Name:  1-[[3-bromo-4-[(2-methyl-3-phenylphenyl)methoxy]phenyl]methyl]piperidine-2-carboxylic acid
    SMILES:  CC1=C(C=CC=C1C2=CC=CC=C2)COC3=C(C=C(C=C3)CN4CCCCC4C(=O)O)Br
    InChIKey: QRXBPPWUGITQLE-UHFFFAOYSA-N
    InChI:  InChI=1S/C27H28BrNO3/c1-19-22(10-7-11-23(19)21-8-3-2-4-9-21)18-32-26-14-13-20(16-24(26)28)17-29-15-6-5-12-25(29)27(30)31/h2-4,7-11,13-14,16,25H,5-6,12show more
    Synonyms: 1-(3-Bromo-4-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylic acid | CHEMBL4099869 | 1-[3-Bromo...
  4. PROTAC PD-1/PD-L1 degrader-1
      Grade & Purity: 
    • ≥98%
    Cas Number: 2447066-37-5
    Formula:  C59H58ClN7O11        Molecular Weight: 1076.59
    SMILES:  O=C(NC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)CCCC(N4CCN(C(C5N(CC6=CC(Cl)=C(OCC7=CC=CC(C8=CC=C9OCCOC9=C8)=C7C)C=C6OCC%10=CC=CC(C#N)=C%10)CCCC5)=O)CC4)show more
  5. PD-1/PD-L1-IN-NP19
      Grade & Purity: 
    • ≥98%
    Cas Number: 2377916-66-8        Compound CID:  154573771
    Formula:  C33H31ClN2O4        Molecular Weight: 555.06
    IUPAC Name:  2-[[5-chloro-2-[(3-cyanophenyl)methoxy]-4-[(2-methyl-3-phenylphenyl)methoxy]phenyl]methylamino]-2-methylpropanoic acid
    SMILES:  CC1=C(C=CC=C1C2=CC=CC=C2)COC3=C(C=C(C(=C3)OCC4=CC(=CC=C4)C#N)CNC(C)(C)C(=O)O)Cl
    InChIKey: YZPKZNFXWGTUGO-UHFFFAOYSA-N
    InChI:  InChI=1S/C33H31ClN2O4/c1-22-26(13-8-14-28(22)25-11-5-4-6-12-25)21-40-31-17-30(39-20-24-10-7-9-23(15-24)18-35)27(16-29(31)34)19-36-33(2,3)32(37)38/h4-1show more
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