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PD-1/PD-L1
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PD-1/PD-L1 inhibitor 1Cas Number: 1675201-83-8 Compound CID: 91663303Formula: C29H33NO5 Molecular Weight: 475.6IUPAC Name: (2S)-1-[[2,6-dimethoxy-4-[(2-methyl-3-phenylphenyl)methoxy]phenyl]methyl]piperidine-2-carboxylic acidSMILES: CC1=C(C=CC=C1C2=CC=CC=C2)COC3=CC(=C(C(=C3)OC)CN4CCCCC4C(=O)O)OCInChIKey: ZBOYJODMIAUJHH-SANMLTNESA-NInChI: show moreSynonyms: (2S)-1-[[2,6-dimethoxy-4-[(2-methyl-3-phenylphenyl)methoxy]phenyl]methyl]piperidine-2-carboxylicacid;(S)-1-(2,6-dimet...
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Pembrolizumab (anti-PD-1), Antibody of programmed cell death 1 (CD279)Associated targets: PDCD1Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; UnconjugatedSpecies reactivity(Reacts with): Cynomolgus monkey, Human Isotype: Human IgG4SPHost species: Human Conjugation: UnconjugatedIUPAC Name: show moreSMILES: CC.CCCCCCCCCCCCC(C)CN(CCCCC=C)CC(CCCCCCCCCCCC)O.CCCCCC=CC=CCCCCCC(C)CN(CCCS)CC(C)CCCCCCC=CC=CCCCC.CCCCN1CCN(CC1)CCCInChIKey: AMOIBCKFWIUEKF-UHFFFAOYSA-NInChI: show moreSynonyms: 1374853-91-4 | 1-butyl-4-propylpiperazine;ethane;1-[hex-5-enyl(2-methyltetradecyl)amino]tetradecan-2-ol;3-[[(8E,10E)-...
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Sulfamethoxypyridazine, Bacterial dihydropteroate synthase inhibitorCas Number: 80-35-3 Compound CID: 5330Formula: C11H12N4O3S Molecular Weight: 280.3IUPAC Name: 4-amino-N-(6-methoxypyridazin-3-yl)benzenesulfonamideSMILES: COC1=NN=C(C=C1)NS(=O)(=O)C2=CC=C(C=C2)NInChIKey: VLYWMPOKSSWJAL-UHFFFAOYSA-NInChI: InChI=1S/C11H12N4O3S/c1-18-11-7-6-10(13-14-11)15-19(16,17)9-4-2-8(12)3-5-9/h2-7H,12H2,1H3,(H,13,15)Synonyms: sulfamethoxypyridazine|80-35-3|Sulphamethoxypyridazine|Midicel|Sulfapyridazine|Depovernil|Sulfalex|Sulfametoxipiridaz...
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Tomivosertib (eFT-508), Inhibitor of CDC like kinase 4;Inhibitor of MAPK interacting serine/threonine kinase 1;Inhibitor of MAPK interacting serine/threonine kinase 2;Inhibitor of serine/threonine kinase 17aCas Number: 1849590-01-7 Compound CID: 118598754Formula: C17H20N6O2 Molecular Weight: 340.38IUPAC Name: 6-[(6-aminopyrimidin-4-yl)amino]-8-methylspiro[2H-imidazo[1,5-a]pyridine-3,1'-cyclohexane]-1,5-dioneSMILES: CC1=C2C(=O)NC3(N2C(=O)C(=C1)NC4=NC=NC(=C4)N)CCCCC3InChIKey: HKTBYUWLRDZAJK-UHFFFAOYSA-NInChI: InChI=1S/C17H20N6O2/c1-10-7-11(21-13-8-12(18)19-9-20-13)16(25)23-14(10)15(24)22-17(23)5-3-2-4-6-17/h7-9H,2-6H2,1H3,(H,22,24)(H3,18,19,20,21)Synonyms: (R)-Pulegone - 90% | 1849590-01-7 | UNII-U2H19X4WBV | 6'-[(6-aminopyrimidin-4-yl)amino]-8'-methyl-2'H-spiro[cyclohexa...
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Tomivosertib (eFT-508), Inhibitor of CDC like kinase 4;Inhibitor of MAPK interacting serine/threonine kinase 1;Inhibitor of MAPK interacting serine/threonine kinase 2;Inhibitor of serine/threonine kinase 17aCas Number: 1849590-01-7 Compound CID: 118598754Formula: C17H20N6O2 Molecular Weight: 340.38IUPAC Name: 6-[(6-aminopyrimidin-4-yl)amino]-8-methylspiro[2H-imidazo[1,5-a]pyridine-3,1'-cyclohexane]-1,5-dioneSMILES: CC1=C2C(=O)NC3(N2C(=O)C(=C1)NC4=NC=NC(=C4)N)CCCCC3InChIKey: HKTBYUWLRDZAJK-UHFFFAOYSA-NInChI: InChI=1S/C17H20N6O2/c1-10-7-11(21-13-8-12(18)19-9-20-13)16(25)23-14(10)15(24)22-17(23)5-3-2-4-6-17/h7-9H,2-6H2,1H3,(H,22,24)(H3,18,19,20,21)Synonyms: Tomivosertib|eFT508|1849590-01-7|EFT-508|Tomivosertib [INN]|Tomivosertib [USAN]|EFT 508|U2H19X4WBV|6-[(6-aminopyrimid...
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Envafolimab (anti-PD-L1), BINDING AGENT of Programmed cell death 1 ligand 1 binding agentAssociated targets: CD274Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; VHH; CHO; ELISA, FACS, Functional assay, Animal Model; UnconjugatedSpecies reactivity(Reacts with): Cynomolgus monkey, Human Isotype: VHHHost species: Human Conjugation: UnconjugatedCas Number: 2102192-68-5Synonyms: B7 H1 antibody | B7 homolog 1 antibody | B7-H1 antibody | B7H antibody | B7H1 antibody | CD 274 antibody | CD-274 ant...
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Spartalizumab (anti-PD-1), Antibody of programmed cell death 1 (CD279)Associated targets: PDCD1Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; UnconjugatedSpecies reactivity(Reacts with): Cynomolgus monkey, Human Isotype: Human IgG4SPHost species: Human Conjugation: UnconjugatedCas Number: 1935694-88-4Synonyms: hPD-1 | Protein PD-1
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Penpulimab (anti-PDCD1), Antibody of programmed cell death 1 (CD279)Associated targets: PDCD1Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; UnconjugatedSpecies reactivity(Reacts with): Human, Rhesus monkey Isotype: Human IgG1Host species: Human Conjugation: UnconjugatedCas Number: 2350298-92-7Synonyms: Anti-PDCD1 / PD-1 / CD279 Reference Antibody (penpulimab) | Penpulimab | CD279 antibody | CD279 antigen antibody | hP...
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Onvatilimab (anti-VISTA)Associated targets: VSIRShort Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; UnconjugatedSpecies reactivity(Reacts with): Cynomolgus monkey, Human, Mouse Isotype: Human IgG1Host species: Human Conjugation: UnconjugatedCas Number: 1969313-51-6Synonyms: Anti-B7-H5 / VISTA Reference Antibody (onvatilimab) | Onvatilimab | JNJ-61610588 | B7 H5 antibody | B7H5 antibody | C...
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Sintilimab (anti-PD-1), ANTAGONIST of Programmed cell death protein 1 antagonistAssociated targets: PDCD1Short Overview: Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; UnconjugatedSpecies reactivity(Reacts with): Cynomolgus monkey, Human Isotype: Human IgG4SPHost species: Human Conjugation: UnconjugatedCas Number: 2072873-06-2Synonyms: IBI 308 | CD279 antibody | CD279 antigen antibody | hPD 1 antibody | hPD l antibody | hPD-1 antibody | hSLE1 antibody...
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evixapodlinCas Number: 2374856-75-2 Compound CID: 139415912Formula: C34H36Cl2N8O4 Molecular Weight: 691.61IUPAC Name: show moreSMILES: COC1=NC(=CN=C1CNCC2CCC(=O)N2)C3=CC=CC(=C3Cl)C4=C(C(=CC=C4)C5=CN=C(C(=N5)OC)CNCC6CCC(=O)N6)ClInChIKey: OIIOPWHTJZYKIL-PMACEKPBSA-NInChI: show moreSynonyms: PD-1/PD-L1-IN 7 | GS-4224
