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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab209925-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$109.90
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Ab209925-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$509.90
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Ab209925-5mg
|
5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,399.90
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Ab209925-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$2,299.90
|
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Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated
| Product Name | XT-M4 (anti-AGER) - Primary antibody, specific to AGER, Human IgG1 |
|---|---|
| Synonyms | Advanced glycosylation end product-specific receptor antibody | Ager antibody | DAMA 358M23.4 antibody | MGC2235 antibody | MGC22357 antibody | RAGE_HUMAN antibody | Receptor for advanced glycation end products antibody | Receptor for advanced glycosylati |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Biochemical and Physiological Mechanisms | Mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. Acts as a mediator of both acute and chronic vascular |
| Host species | Human |
| Specificity | AGER |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
XT-M4 (anti-AGER) is a humanized anti-RAGE antibody with potential to treat acute and chronic inflammatory conditions. |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 150 kDa |
| Purification Method | Protein A purified |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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XT-M4 (anti-AGER) (Ab209925) - ELISA
Immobilized Recombinant Human AGER-ECD-His protein at 2.0 μg/mL can bind XT-M4 (anti-AGER) (Ab209925) with the EC₅₀ of 84.59 ng/mL.
XT-M4 (anti-AGER) (Ab209925) - SEC
The purity of XT-M4 (anti-AGER) (Ab209925) is more than 95% verified by HPLC.