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XT-M4 (anti-AGER) - Primary antibody, specific to AGER, Human IgG1

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human,Mouse
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab209925
Grouped product items
SKU Size
Availability
Price Qty
Ab209925-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$109.90
Ab209925-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$509.90
Ab209925-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,399.90
Ab209925-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,299.90

Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name XT-M4 (anti-AGER) - Primary antibody, specific to AGER, Human IgG1
Synonyms Advanced glycosylation end product-specific receptor antibody | Ager antibody | DAMA 358M23.4 antibody | MGC2235 antibody | MGC22357 antibody | RAGE_HUMAN antibody | Receptor for advanced glycation end products antibody | Receptor for advanced glycosylati
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Biochemical and Physiological Mechanisms Mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. Acts as a mediator of both acute and chronic vascular
Host species Human
Specificity AGER
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

XT-M4 (anti-AGER) is a humanized anti-RAGE antibody with potential to treat acute and chronic inflammatory conditions.

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 150 kDa
Purification Method Protein A purified
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

AGER Tchem Advanced glycosylation end product-specific receptor (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

XT-M4 (anti-AGER) (Ab209925) - ELISA
Immobilized Recombinant Human AGER-ECD-His protein at 2.0 μg/mL can bind XT-M4 (anti-AGER) (Ab209925) with the EC₅₀ of 84.59 ng/mL.

XT-M4 (anti-AGER) (Ab209925) - SEC
The purity of XT-M4 (anti-AGER) (Ab209925) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Solution Calculators

Reviews

Customer Reviews

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