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Urelumab (anti-TNFRSF9) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to TNFRSF9, >95%, high purity, Human IgG4SP, Antibody of 4-1BB, Antibody of 4-1BB

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human
  • Isotype: Human IgG4SP
  • Conjugation: Unconjugated
In stock
Item Number
Ab170654
Grouped product items
SKU Size
Availability
Price Qty
Ab170654-100μg
100μg
10
$129.90
Ab170654-1mg
1mg
4
$627.90
Ab170654-5mg
5mg
1
$1,857.90
Ab170654-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,607.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Urelumab (anti-TNFRSF9) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to TNFRSF9, >95%, high purity, Human IgG4SP, Antibody of 4-1BB
Synonyms 4 1BB antibody | 4 1BB ligand receptor antibody | 4-1BB ligand receptor antibody | 4-1BB Ligand Receptor T Cell antibody | 4-1BB, mouse, homolog of antibody | Antigen 4-1BB Homolog antibody | CD 137 antibody | CD137 antibody | CD137 antigen antibody | CDw
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity TNFRSF9
Application ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR)
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type AGONIST
Mechanism of action Antibody of 4-1BB
Product Description

Urelumab is a humanized IgG4 monoclonal antibody used as a CD137 agonist to enhance the antitumor activity of T cells and natural killer cells, and to enhance the cytotoxic activity of Rituximab. Urelumab can be used in studies of diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL), and other types of non-Hodgkin lymphoma (NHL).
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Antibody Type Primary antibody
Clonality Recombinant
Isotype Human IgG4SP
Light Chain Type kappa
SDS-PAGE 26.9 kDa (Light Chain) & 52.2 kDa (Heavy Chain), under reducing conditions; 180.9 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Source CHO supernatant
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 934823-49-1

Associated Targets(Human)

TNFRSF9 Tbio Tumor necrosis factor receptor superfamily member 9 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Urelumab (anti-TNFRSF9) (Ab170654) - ELISA
Immobilized N-His-HSA-TNFSF9/4-1BB-ECD at 2 μg/mL can bind Urelumab (anti-TNFRSF9) (Ab170654) with the EC50 of 12.68 ng/mL.


Urelumab (anti-TNFRSF9) (Ab170654) - SEC
The purity of Urelumab (anti-TNFRSF9) (Ab170654) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0303034 Certificate of Analysis Mar 08, 2024 Ab170654
ZJ24F0303036 Certificate of Analysis Mar 08, 2024 Ab170654
ZJ24F0303035 Certificate of Analysis Mar 08, 2024 Ab170654

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