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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab170654-100μg
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100μg |
10
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$129.90
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Ab170654-1mg
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1mg |
4
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$627.90
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Ab170654-5mg
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5mg |
1
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$1,857.90
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Ab170654-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$2,607.90
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Urelumab (anti-TNFRSF9) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to TNFRSF9, >95%, high purity, Human IgG4SP, Antibody of 4-1BB |
|---|---|
| Synonyms | 4 1BB antibody | 4 1BB ligand receptor antibody | 4-1BB ligand receptor antibody | 4-1BB Ligand Receptor T Cell antibody | 4-1BB, mouse, homolog of antibody | Antigen 4-1BB Homolog antibody | CD 137 antibody | CD137 antibody | CD137 antigen antibody | CDw |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | TNFRSF9 |
| Application | ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | AGONIST |
| Mechanism of action | Antibody of 4-1BB |
| Product Description |
Urelumab is a humanized IgG4 monoclonal antibody used as a CD137 agonist to enhance the antitumor activity of T cells and natural killer cells, and to enhance the cytotoxic activity of Rituximab. Urelumab can be used in studies of diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL), and other types of non-Hodgkin lymphoma (NHL). |
| Antibody Type | Primary antibody |
|---|---|
| Clonality | Recombinant |
| Isotype | Human IgG4SP |
| Light Chain Type | kappa |
| SDS-PAGE | 26.9 kDa (Light Chain) & 52.2 kDa (Heavy Chain), under reducing conditions; 180.9 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Source | CHO supernatant |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 934823-49-1 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Urelumab (anti-TNFRSF9) (Ab170654) - ELISA
Immobilized N-His-HSA-TNFSF9/4-1BB-ECD at 2 μg/mL can bind Urelumab (anti-TNFRSF9) (Ab170654) with the EC50 of 12.68 ng/mL.
Urelumab (anti-TNFRSF9) (Ab170654) - SEC
The purity of Urelumab (anti-TNFRSF9) (Ab170654) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Mar 08, 2024 | Ab170654 | |
| Certificate of Analysis | Mar 08, 2024 | Ab170654 | |
| Certificate of Analysis | Mar 08, 2024 | Ab170654 |
Starting at $79.90