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Tanezumab (anti-NGF) - Primary antibody, specific to NGF, Human IgG2, INHIBITOR of Beta-nerve growth factor inhibitor, INHIBITOR of Beta-nerve growth factor inhibitor

COA COA
    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG2
  • Conjugation: Unconjugated
In stock
Item Number
Ab175666
Grouped product items
SKU Size
Availability
 Price Qty
Ab175666-100μg
100μg
10
$39.90
Ab175666-1mg
1mg
4
$179.90
Ab175666-5mg
5mg
1
$449.90
Ab175666-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$719.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG2; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

View related series
Click to view target information: NGF
Accession#:P01138 (8) Beta-NGF (4) Gene ID:4803 (8) NGF (8) Receptor Tyrosine Kinase (1260)

Basic Description

Product Name Tanezumab (anti-NGF) - Primary antibody, specific to NGF, Human IgG2, INHIBITOR of Beta-nerve growth factor inhibitor
Synonyms Beta nerve growth factor antibody | Beta NGF antibody | Beta-nerve growth factor antibody | Beta-NGF antibody | HSAN5 antibody | MGC161426 antibody | MGC161428 antibody | Nerve growth factor (beta polypeptide) antibody | Nerve growth factor antibody | Ner
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity NGF
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action INHIBITOR of Beta-nerve growth factor inhibitor
Product Description

Tanezumab (anti-NGF) is a humanized anti-NGF mAb with high affinity and specificity. Tanezumab (anti-NGF) blocks NGF binding to its receptors, p75 and TrkA, in the peripheral nervous system. Tanezumab (anti-NGF) can be used in studies of acute and chronic pain such as osteoarthritis, knee and neuralgia, as well as post-herpetic neuralgia.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Isotype Human IgG2
Light Chain Type kappa
SDS-PAGE 26.7 kDa (Light Chain) & 51.0 kDa (Heavy Chain), under reducing conditions; 194.4 kDa, under non-reducing conditions.
Purification Method Protein A purified
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle.
CAS 880266-57-9

Associated Targets(Human)

NGF Tchem Beta-nerve growth factor (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Tanezumab (anti-NGF) (Ab175666) - ELISA
Immobilized Human NGFB-His at 2.0 μg/mL can bind Tanezumab (anti-NGF) (Ab175666) with the EC₅₀ of 0.30 μg/mL.

Tanezumab (anti-NGF) (Ab175666) - SEC
The purity of Tanezumab (anti-NGF) (Ab175666) is more than 95% verified by HPLC.

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0404822 Certificate of Analysis Apr 24, 2024 Ab175666
ZJ24F0404821 Certificate of Analysis Apr 24, 2024 Ab175666
ZJ24F0404820 Certificate of Analysis Apr 24, 2024 Ab175666

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