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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab190138-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$109.90
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Ab190138-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$519.90
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Ab190138-5mg
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5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,299.90
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Ab190138-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$2,079.90
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Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated
| Product Name | TAK-701 (anti-HGF) - Primary antibody, specific to HGF, Human IgG1 |
|---|---|
| Synonyms | DFNB39 antibody | F TCF antibody | Fibroblast derived tumor cytotoxic factor antibody | Hepatocyte growth factor (hepapoietin A | scatter factor) antibody | Hepatocyte growth factor antibody | Hepatocyte growth factor beta chain antibody | Hepatocyte grow |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Biochemical and Physiological Mechanisms | Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting i |
| Host species | Human |
| Specificity | HGF |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
TAK-701 (anti-HGF) is a humanized monoclonal antibody directed against human hepatocyte growth factor (HGF) with potential antineoplastic activity. It reverses gefitinib resistance in non-small-cell lung cancer. |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 153.8 kDa |
| Purification Method | Protein A purified |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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TAK-701 (anti-HGF) (Ab190138) - ELISA
Immobilized Recombinant Human HGF protein (rp175908) at 2.0 μg/mL can bind TAK-701 (anti-HGF) (Ab190138) with the EC50 of 17.0 ng/mL.
TAK-701 (anti-HGF) (Ab190138) - SEC
The purity of TAK-701 (anti-HGF) (Ab190138) is more than 95% verified by HPLC.
Starting at $59.90
Starting at $69.90