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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab182704-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$109.90
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Ab182704-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$519.90
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Ab182704-5mg
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5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,299.90
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Ab182704-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$2,079.90
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Purity≥95% (SDS-PAGE&SEC); Endotoxin Level≤1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | STX-100 (anti-Integrin aVb6) - Primary antibody, specific to ITGAV; ITGB6, Human IgG1, INHIBITOR of Integrin alpha-V/beta-6 inhibitor |
|---|---|
| Synonyms | antigen identified by monoclonal antibody L230 antibody | CD 51 antibody | CD51 antibody | DKFZp686A08142 antibody | Integrin alpha five antibody | integrin alpha V beta 3 antibody | Integrin alpha-5 antibody | integrin alpha-V antibody | Integrin alpha-V |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | ITGAV; ITGB6 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of Integrin alpha-V/beta-6 inhibitor |
| Product Description |
STX-100 (anti-Integrin aVb6 (ITGAV & ITGB6)) is a humanized monoclonal antibody directed against the alpha v beta 6 (αvβ6) integrin. It has a potential to be used in research on Idiopathic Pulmonary Fibrosis (IPF). |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 145.12 kDa |
| Purification Method | Protein A purified |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 1439902-67-6 |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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STX-100 (anti-Integrin aVb6) (Ab182704) - Flow Cytometry
Flow Cytometry analysis of MCF-7 cells labelling Integrin aVb6 (red) with STX-100 (anti-Integrin aVb6) (Ab182704) at 1.0 μg/mL for 1 hour at 4°C. Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
STX-100 (anti-Integrin aVb6) (Ab182704) - ELISA
Immobilized Human Integrin alpha V beta 6 (ITGAV&ITGB6) at 2.0 μg/mL can bind STX-100 (anti-Integrin aVb6) (Ab182704) with the EC₅₀ of 131.5 ng/mL.
STX-100 (anti-Integrin aVb6) (Ab182704) - SEC
The purity of STX-100 (anti-Integrin aVb6) (Ab182704) is more than 95% verified by HPLC.