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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab175649-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$69.90
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Ab175649-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$339.90
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Ab175649-5mg
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5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$869.90
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Ab175649-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,379.90
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Purity≥95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Rovelizumab (anti-CD11a&CD18) - Primary antibody, specific to ITGAL; ITGB2, Human IgG4, Antibody of integrin; alpha L subunit (antigen CD11A (p180); lymphocyte function-associated antigen 1; alpha polypeptide);Antibody of integrin; beta 2 subunit (complem |
|---|---|
| Synonyms | Lymphocyte function associated antigen, type 1, alpha subunit antibody | Antigen CD11A (p180), lymphocyte function associated antigen 1, alpha polypeptide antibody | Antigen CD11A antibody | CD 11a antibody | CD11 antigen-like family member A antibody | C |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Biochemical and Physiological Mechanisms | CD11a: Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granuloc |
| Host species | Human |
| Specificity | ITGAL; ITGB2 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | ANTAGONIST |
| Mechanism of action | Antibody of integrin; alpha L subunit (antigen CD11A (p180); lymphocyte function-associated antigen 1; alpha polypeptide);Antibody of integrin; beta 2 subunit (complement component 3 receptor 3 and 4 subunit) |
| Product Description |
Rovelizumab (anti-CD11a&CD18) is a humanized monoclonal leukointegrin antibody. Rovelizumab (anti-CD11a&CD18) is a monoclonal antibody directed against the CD11/CD18 cell adhesion proteins. Rovelizumab (anti-CD11a&CD18) can be used for research of multiple sclerosis (MS), hemorrhagic shock, myocardial infarction (MI) and stroke. |
| Isotype | Human IgG4 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 145.98 kDa |
| Purification Method | Protein A purified |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon delivery aliquot. Avoid freeze/thaw cycle. |
| CAS | 339086-79-2 |
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