Determine the necessary mass, volume, or concentration for preparing a solution.
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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab175715-100μg
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100μg |
10
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$59.90
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Ab175715-1mg
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1mg |
4
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$267.90
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Ab175715-5mg
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5mg |
1
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$687.90
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Ab175715-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$1,077.90
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level< 0.01EU/μg ; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Polatuzumab (anti-CD79b) - Primary antibody, specific to CD79B, >95% (SDS-PAGE&SEC), high purity, Human IgG1 |
|---|---|
| Synonyms | AGM6 antibody | B cell antigen receptor complex associated protein beta chain antibody | B cell specific glycoprotein B29 antibody | B-cell antigen receptor complex-associated protein beta chain antibody | B-cell-specific glycoprotein B29 antibody | B29 a |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | CD79B |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Recombinant, Validated |
| Product Description |
Polatuzumab (anti-CD79b) is a monoclonal antibody, which targets CD79b that is found on the surface of B cells. Polatuzumab (anti-CD79b) sticks to the CD79b protein and delivers the chemotherapy compound into the cell. Polatuzumab (anti-CD79b) can be used to synthesize Polatuzumab Vedotin, which is an antibody-drug conjugate (ADC) targeting CD79b. |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 27.4 kDa (Light Chain) & 51.8 kDa (Heavy Chain), under reducing conditions; 180.0 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% (SDS-PAGE&SEC) |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 2279068-37-8 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Polatuzumab (anti-CD79b) (Ab175715) - ELISA
Immobilized hu-CD79b-His at 2 μg/mL can bind Polatuzumab (anti-CD79b) (Ab175715) with the EC₅₀ of 4.09 ng/mL.
Polatuzumab (anti-CD79b) (Ab175715) - SEC
The purity of Polatuzumab (anti-CD79b) (Ab175715) is more than 95% verified by HPLC.
Recombinant Human CD79B Protein (rp176729) - ELISA
Immobilized Recombinant Human CD79B Protein (rp176729) at 1.0 μg/mL can bind Polatuzumab (anti-CD79b) (Ab175715) with the EC50 of 11.08 ng/mL.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Mar 08, 2024 | Ab175715 | |
| Certificate of Analysis | Mar 08, 2024 | Ab175715 | |
| Certificate of Analysis | Mar 08, 2024 | Ab175715 |