Determine the necessary mass, volume, or concentration for preparing a solution.
This is a demo store. No orders will be fulfilled.
| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
|
Ab209755-100μg
|
100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$109.90
|
|
|
Ab209755-1mg
|
1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$509.90
|
|
|
Ab209755-5mg
|
5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,399.90
|
|
|
Ab209755-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$2,299.90
|
|
Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated
| Product Name | KHK patent anti-CRTH2 (anti-CRTH2) - Primary antibody, specific to PTGDR2, Human IgG1 |
|---|---|
| Synonyms | CD294 antibody | CD294 antigen antibody | Chemoattractant receptor homologous molecule expressed on Th2 cells antibody | chemoattractant receptor-homologous antibody | Chemoattractant receptor-homologous molecule expressed on Th2 cells antibody | CRTH 2 a |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Biochemical and Physiological Mechanisms | Orphan receptor. |
| Host species | Human |
| Specificity | PTGDR2 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
KHK patent anti-CRTH2 (anti-CRTH2) is a monoclonal antibody against a transmembrane G-protein-coupled receptor (GPR44, also known as CRTH2, PTGDR2,or CD294) with the potential to treat asthma. |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 150 kDa |
| Purification Method | Protein A purified |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
KHK patent anti-CRTH2 (anti-CRTH2) (Ab209755) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CRTH2 with KHK patent anti-CRTH2 (anti-CRTH2) (Ab209755) conjugated with biotin (right panel) compared with Human IgG (Biotin) (Ab180314) - Isotype Control (left panel) and detected with SA-PE (rp156150).
KHK patent anti-CRTH2 (anti-CRTH2) (Ab209755) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CRTH2 (red) with KHK patent anti-CRTH2 (anti-CRTH2) (Ab209755) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, Human IgG (Biotin) (Ab180314). Black - Unlabelled control, cells without incubation with primary antibody.
KHK patent anti-CRTH2 (anti-CRTH2) (Ab209755) - Flow Cytometry
Flow Cytometry analysis of NCI-H716 cells labelling CRTH2 at 1×10⁵ cell/well can bind KHK patent anti-CRTH2 (anti-CRTH2) (Ab209755), with the EC₅₀ is 37.55 μg/mL.
KHK patent anti-CRTH2 (anti-CRTH2) (Ab209755) - SEC
The purity of KHK patent anti-CRTH2 (anti-CRTH2) (Ab209755) is more than 95% verified by HPLC.