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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab110789-10μg
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10μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$49.90
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Ab110789-50μg
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50μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$129.90
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Ab110789-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$179.90
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Ab110789-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$639.90
|
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mAb (R1-2); Rat anti Mouse Integrin alpha 4/CD49d Antibody; Flow, FA, IHC-F, IP; Unconjugated
| Product Name | Integrin alpha 4/CD49d Rat mAb - Primary antibody, specific to Integrin alpha 4/CD49d, Rat IgG2b |
|---|---|
| Synonyms | 269C wild type antibody | Antigen CD49D, alpha 4 subunit of VLA 4 receptor antibody | CD49 antigen like family member D antibody | CD49 antigen-like family member D antibody | CD49d antibody | IA4 antibody | Integrin alpha 4 antibody | Integrin alpha 4 su |
| Specifications & Purity | Carrier Free, ExactAb™, Low Endotoxin, Azide Free, Validated, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Biochemical and Physiological Mechanisms | Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recogni |
| Host species | Rat |
| Specificity | Integrin alpha 4/CD49d |
| Immunogen | AKR/Cum mouse Spontaneous T lymphoma line TK1 |
| Positive Control | Flow Cyt: Human whole peripheral blood cells. IHC-Fr: Human tonsil tissue. ICC/IF: Wild-type HAP-1 cells. |
| Conjugation | Unconjugated |
| Grade | Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Validated |
| Product Description |
Rat anti Mouse Integrin alpha 4/CD49d Antibody, Monoclonal (R1-2), could be used for Flow, FA, IHC-F, IP and so on.
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| Isotype | Rat IgG2b |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 150 kDa |
| Purification Method | Protein A/G purified |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 2-8°C short term (1 month). Store at -80°C long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Integrin alpha 4/CD49d Rat mAb (Ab110789) - Flow Cytometry
Flow Cytometry analysis of mouse splenocytes cells labelling Integrin alpha 4/CD49d with Integrin alpha 4/CD49d Rat mAb (Ab110789) conjugated with biotin (right panel) at 0.2 μg/mL for 1 hour at 4°C, compared with Rat IgG Isotype Control Antibody (Biotin) (Ab180310) (left panel) and detected with SA-PE (rp156150).
Integrin alpha 4/CD49d Rat mAb (Ab110789) - Flow Cytometry
Flow Cytometry analysis of mouse splenocytes cells labelling Integrin alpha 4/CD49d (red) with Integrin alpha 4/CD49d Rat mAb (Ab110789) conjugated with biotin at 0.2 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Rat IgG Isotype Control Antibody (Biotin) (Ab180310). Black - Unlabelled control, cells without incubation with primary antibody.
| Application | Dilution info |
|---|---|
| Functional Assay | Use at an assay dependent concentration. |
| IP | Use at an assay dependent concentration. |
| Flow Cytometry | Use at an assay dependent concentration. |
| IHC-F | Use at an assay dependent concentration. |