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Inclacumab (anti-CD62p) - Primary antibody, specific to SELP, >95%, high purity, Human IgG4SP, Antibody of selectin P (CD62), Antibody of selectin P (CD62)

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human,Rat
  • Isotype: Human IgG4SP
  • Conjugation: Unconjugated
In stock
Item Number
Ab175562
Grouped product items
SKU Size
Availability
Price Qty
Ab175562-100μg
100μg
10
$119.90
Ab175562-1mg
1mg
4
$569.90
Ab175562-5mg
5mg
1
$1,489.90
Ab175562-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,379.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Inclacumab (anti-CD62p) - Primary antibody, specific to SELP, >95%, high purity, Human IgG4SP, Antibody of selectin P (CD62)
Synonyms CD62 antigen-like family member P | GMP-140 | Granule membrane protein 140 | LECAM3 | Leukocyte-endothelial cell adhesion molecule 3 | PADGEM | Platelet activation dependent granule-external membrane protein
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity SELP
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type ANTAGONIST
Mechanism of action Antibody of selectin P (CD62)
Product Description

Inclacumab (anti-CD62p) is a humanized monoclonal IgG4 antibody selectively targets P-selectin with a Kd value of 9.9 nM. Inclacumab (anti-CD62p) inhibits P-selectin glycoprotein ligand 1 (PSGL-1) mimetic peptide bind with P-selectin with an IC50 value of 1.9 µg/mL and strongly inhibits cell adhesion.

Product Properties

Isotype Human IgG4SP
Light Chain Type kappa
SDS-PAGE 26.8 kDa (Light Chain) & 52.0 kDa (Heavy Chain), under reducing conditions; 178.3 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1256258-86-2

Associated Targets(Human)

SELP Tclin P-selectin (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Inclacumab (anti-CD62p) (Ab175562) - ELISA
Immobilized Human P-Selectin/CD62p-Fc Tag at 2.0 μg/mL can bind Inclacumab (anti-CD62p) (Ab175562) with the EC₅₀ of 8.58 ng/mL.

Inclacumab (anti-CD62p) (Ab175562) - SEC
The purity of Inclacumab (anti-CD62p) (Ab175562) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0303921 Certificate of Analysis Mar 29, 2024 Ab175562
ZJ24F0303920 Certificate of Analysis Mar 29, 2024 Ab175562
ZJ24F0303919 Certificate of Analysis Mar 29, 2024 Ab175562

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