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Etaracizumab (anti-Integrin aVb3) - Primary antibody, specific to Integrin aVb3 (ITGAV & ITGB3), >95%, high purity, Human IgG1, Antibody of integrin αVβ3, Antibody of integrin αVβ3

COA COA
    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab175533
Grouped product items
SKU Size
Availability
 Price Qty
Ab175533-100μg
100μg
10
$79.90
Ab175533-1mg
1mg
4
$379.90
Ab175533-5mg
5mg
1
$979.90
Ab175533-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,799.90
Wish List
Bulk Order  SDS  DATASHEET  Specification Sheet

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

View related series
Click to view target information: ITGB3 Click to view target information: ITGAV
Accession#:P05106 (9) Accession#:P06756 (5) Gene ID:3685 (5) Gene ID:3690 (9) Integrin aVb3 (1) integrin αVβ3 Antibody (1) ITGAV (5) ITGB3 (9)

Basic Description

Product Name Etaracizumab (anti-Integrin aVb3) - Primary antibody, specific to Integrin aVb3 (ITGAV & ITGB3), >95%, high purity, Human IgG1, Antibody of integrin αVβ3
Synonyms antigen identified by monoclonal antibody L230 antibody | CD 51 antibody | CD51 antibody | DKFZp686A08142 antibody | Integrin alpha five antibody | integrin alpha V beta 3 antibody | Integrin alpha-5 antibody | integrin alpha-V antibody | Integrin alpha-V
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity Integrin aVb3 (ITGAV & ITGB3)
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type ANTAGONIST
Mechanism of action Antibody of integrin αVβ3
Product Description

Etaracizumab (anti-Integrin aVb3) is an αvβ3 integrin IgG1 monoclonal antibody. Etaracizumab (anti-Integrin aVb3) inhibits angiogenesis and melanoma tumor growth. Etaracizumab (anti-Integrin aVb3) can be used to research anticancer.

Product Properties

Isotype Human IgG1
Light Chain Type kappa
SDS-PAGE 26.2 kDa (Light Chain) & 51.4 kDa (Heavy Chain), under reducing conditions; 185.3 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 892553-42-3

Associated Targets(Human)

ITGB3 Tclin Integrin beta-3 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
ITGAV Tchem Integrin alpha-V (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
ITGAV Tchem Vitronectin receptor alpha (65 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ITGB3 Tclin Integrin alpha-V/beta-3 (2708 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ITGB3 Tclin Integrin alpha-IIb/beta-3 (3481 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ITGAV Tchem Integrin alpha-V/beta-5 (589 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ITGAV Tchem Integrin alpha-V/beta-6 (509 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ITGB3 Tclin Fibronectin receptor (Integrin alpha-5/beta-1 and alpha-V/beta-3) (39 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ITGB3 Tclin Integrin alpha-V/beta-3 and alpha-IIb/beta 3 (49 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ITGB3 Tclin Integrin alpha-2/beta-3 (21 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ITGAV Tchem Integrin alpha-V/beta-8 (181 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ITGAV Tchem Integrin alpha-V/alpha-5 (6 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ITGB3 Tclin Integrin alpha-3/beta-3 (47 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Etaracizumab (anti-Integrin aVb3) (Ab175533) - Flow Cytometry
Flow Cytometry analysis of HUVEC cells labelling Integrin aVb3 (red) with Etaracizumab (anti-Integrin aVb3) (Ab175533). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Etaracizumab (anti-Integrin aVb3) (Ab175533) - SEC
The purity of Etaracizumab (anti-Integrin aVb3) (Ab175533) is more than 95% verified by HPLC.

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0303915 Certificate of Analysis Mar 29, 2024 Ab175533
ZJ24F0303914 Certificate of Analysis Mar 29, 2024 Ab175533
ZJ24F0303913 Certificate of Analysis Mar 29, 2024 Ab175533

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