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Emapalumab (anti-IFNγ) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to IFNG, >95%, high purity, Human IgG1, INHIBITOR of Interferon gamma inhibitor, INHIBITOR of Interferon gamma inhibitor

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human
  • Isotype: Human IgG1
  • Conjugation: Unconjugated
In stock
Item Number
Ab169274
Grouped product items
SKU Size
Availability
Price Qty
Ab169274-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$49.90
Ab169274-1mg
1mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$207.90
Ab169274-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$627.90
Ab169274-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,077.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Emapalumab (anti-IFNγ) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to IFNG, >95%, high purity, Human IgG1, INHIBITOR of Interferon gamma inhibitor
Synonyms Recombinant Emapalumab Antibody | NI-0501 | Gamifant | Anti-IFNg Reference Antibody (emapalumab) | AF 1 antibody | AF-1 antibody | AF1 antibody | IFGR 2 antibody | IFGR2 antibody | IFN gamma Receptor beta antibody | IFN-gamma receptor 2 antibody | IFN-gam
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity IFNG
Application ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR)
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action INHIBITOR of Interferon gamma inhibitor
Product Description

Emapalumab (anti-IFNγ), a monoclonal antibody directed against IFNγ, is the first global approval for the treatment of pediatric and adult patients with primary hemophagocytic lymphohistiocytosis (HLH) with refractory.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Product Properties

Antibody Type Primary antibody
Clonality Recombinant
Isotype Human IgG1
Light Chain Type lambda
SDS-PAGE 28.2 kDa (Light Chain) & 50.8 kDa (Heavy Chain), under reducing conditions; 176.0 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Source CHO supernatant
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1709815-23-5

Associated Targets(Human)

IFNG Tclin Interferon gamma (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Emapalumab (anti-IFNγ) (Ab169274) - ELISA
Immobilized Recombinant Human IFN-gamma Protein (rp156182) at 1 μg/mL can bind Emapalumab (anti-IFNγ) (Ab169274) with the EC50 of 25.95 ng/mL.

Emapalumab (anti-IFNγ) (Ab169274) - SEC
The purity of Emapalumab (anti-IFNγ) (Ab169274) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F0800897 Certificate of Analysis Aug 25, 2023 Ab169274
ZJ23F0800896 Certificate of Analysis Aug 25, 2023 Ab169274

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