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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab169274-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$49.90
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Ab169274-1mg
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1mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$207.90
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Ab169274-5mg
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5mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$627.90
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Ab169274-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,077.90
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Emapalumab (anti-IFNγ) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to IFNG, >95%, high purity, Human IgG1, INHIBITOR of Interferon gamma inhibitor |
|---|---|
| Synonyms | Recombinant Emapalumab Antibody | NI-0501 | Gamifant | Anti-IFNg Reference Antibody (emapalumab) | AF 1 antibody | AF-1 antibody | AF1 antibody | IFGR 2 antibody | IFGR2 antibody | IFN gamma Receptor beta antibody | IFN-gamma receptor 2 antibody | IFN-gam |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | IFNG |
| Application | ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of Interferon gamma inhibitor |
| Product Description |
Emapalumab (anti-IFNγ), a monoclonal antibody directed against IFNγ, is the first global approval for the treatment of pediatric and adult patients with primary hemophagocytic lymphohistiocytosis (HLH) with refractory. |
| Antibody Type | Primary antibody |
|---|---|
| Clonality | Recombinant |
| Isotype | Human IgG1 |
| Light Chain Type | lambda |
| SDS-PAGE | 28.2 kDa (Light Chain) & 50.8 kDa (Heavy Chain), under reducing conditions; 176.0 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Source | CHO supernatant |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 1709815-23-5 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Emapalumab (anti-IFNγ) (Ab169274) - ELISA
Immobilized Recombinant Human IFN-gamma Protein (rp156182) at 1 μg/mL can bind Emapalumab (anti-IFNγ) (Ab169274) with the EC50 of 25.95 ng/mL.
Emapalumab (anti-IFNγ) (Ab169274) - SEC
The purity of Emapalumab (anti-IFNγ) (Ab169274) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Aug 25, 2023 | Ab169274 | |
| Certificate of Analysis | Aug 25, 2023 | Ab169274 |
Starting at $29.90
Starting at $39.90
Starting at $109.90
Starting at $109.90