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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab169272-100μg
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100μg |
10
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$59.90
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Ab169272-1mg
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1mg |
4
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$267.90
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Ab169272-5mg
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5mg |
1
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$807.90
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Ab169272-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$1,227.90
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<0.01EU/μg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Elotuzumab (anti-SLAMF7) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to SLAMF7, >95%, high purity, Human IgG1, Antibody of CS1 (CD319) |
|---|---|
| Synonyms | Recombinant Elotuzumab Antibody | Elotuzumab | HuLuc 63 | PDL 063 | BMS 901608 | Elotuzumab (anti-SLAMF7) | BMS-901608 | PDL063 | HuLuc63 | Empliciti | 19A antibody | 19A24 protein antibody | CD 319 antibody | CD2 like receptor activating cytotoxic cells |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | SLAMF7 |
| Application | ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | Antibody of CS1 (CD319) |
| Product Description |
Elotuzumab is a humanized monoclonal antibody that binds human signaling lymphocytic activation molecule F7 (hSLAMF7, also known as CS1, CD319, or CRACC). Elotuzumab shows a dual mechanism of action that includes the direct activation of natural killer (NK) cells and the induction of NK cell–mediated antibody-dependent cellular cytotoxicity. |
| Antibody Type | Primary antibody |
|---|---|
| Clonality | Recombinant |
| Isotype | Human IgG1 |
| Light Chain Type | kappa |
| SDS-PAGE | 27.1 kDa (Light Chain) & 52.3 kDa (Heavy Chain), under reducing conditions; 173.0 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Source | CHO supernatant |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 915296-00-3 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Elotuzumab (anti-SLAMF7) (Ab169272) - ELISA
Immobilized huSLAMF7-Fc at 2 μg/mL can bind Elotuzumab (anti-SLAMF7) (Ab169272) with the EC₅₀ of 18.15 ng/mL.
Elotuzumab (anti-SLAMF7) (Ab169272) - SEC
The purity of Elotuzumab (anti-SLAMF7) (Ab169272) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Mar 08, 2024 | Ab169272 | |
| Certificate of Analysis | Mar 08, 2024 | Ab169272 | |
| Certificate of Analysis | Mar 08, 2024 | Ab169272 |
Starting at $109.90
Starting at $109.90