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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab175470-100μg
|
100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$89.90
|
|
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Ab175470-1mg
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1mg |
5
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$449.90
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Ab175470-5mg
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5mg |
1
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$1,189.90
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|
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Ab175470-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,899.90
|
|
Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Bermekimab (anti-IL-1a) - Primary antibody, specific to IL1A, >95%, high purity, Human IgG1, INHIBITOR of Interleukin-1 alpha inhibitor |
|---|---|
| Synonyms | BAF antibody | FAF antibody | Hematopoietin 1 antibody | Hematopoietin-1 antibody | IL 1 alpha antibody | IL 1A antibody | IL-1 alpha antibody | Il-1a antibody | IL1 ALPHA antibody | IL1 antibody | IL1A antibody | IL1A_HUMAN antibody | IL1F1 antibody | In |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | IL1A |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of Interleukin-1 alpha inhibitor |
| Product Description |
Bermekimab (anti-IL-1a) is a human monoclonal antibody that targets interleukin-1alpa (IL-1α). Bermekimab (anti-IL-1a) prevents tumour-related inflammation. |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 145.34 kDa |
| Purification Method | Protein A purified |
| Purity | >95% |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 1401965-15-8 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Bermekimab (anti-IL-1a) (Ab175470) - ELISA
Immobilized Recombinant human IL-1 alpha protein (rp156178) at 1.0 μg/mL can bind Bermekimab (anti-IL-1a) (Ab175470) with the EC₅₀ of 20.80 ng/mL.
Bermekimab (anti-IL-1a) (Ab175470) - SEC
The purity of Bermekimab (anti-IL-1a) (Ab175470) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Dec 13, 2023 | Ab175470 | |
| Certificate of Analysis | Dec 13, 2023 | Ab175470 |