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Abbott patent anti-NGR (anti-NGR) - Primary antibody, specific to RTN4R, Human IgG2SA

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human,Rat
  • Isotype: Human IgG1-REM-FEA
  • Conjugation: Unconjugated
In stock
Item Number
Ab209758
Grouped product items
SKU Size
Availability
Price Qty
Ab209758-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$109.90
Ab209758-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$509.90
Ab209758-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,399.90
Ab209758-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,299.90

Purity≥90% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1-REM-FEA; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Abbott patent anti-NGR (anti-NGR) - Primary antibody, specific to RTN4R, Human IgG2SA
Synonyms NgR antibody | Nogo 66 receptor antibody | Nogo receptor antibody | Nogor antibody | Reticulon 4 receptor antibody | Rtn4r antibody | UNQ330/PRO526 antibody | NgR | NgR1 | Nogo R | Nogo receptor | Nogo-66 receptor | NogoR | Anti-Nogo Receptor/NgR Antibody
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥90%(SDS-PAGE&SEC-HPLC), See COA
Biochemical and Physiological Mechanisms 4-1BB: Receptor for TNFSF14/4-1BBL. Possibly active during T cell activation. PD-L1: Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction
Host species Human
Specificity RTN4R
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

Acasunlimab (anti-4-1BB&PD-L1) is a bispecific antibody (bsAb) targeting PD-L1 and 4-1BB. Acasunlimab (anti-4-1BB&PD-L1) enhances T-cell and NK-cell function through conditional 4-1BB stimulation while constitutively blocking the PD-1/PD-L1 inhibitory axis. Acasunlimab (anti-4-1BB&PD-L1) can be used in research of cancer.

Product Properties

Isotype Human IgG2SA
Light Chain Type lambdaC2
SDS-PAGE 150 kDa
Purification Method Protein A purified
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

RTN4R Tbio Reticulon-4 receptor (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Images

Abbott patent anti-NGR (anti-NGR) (Ab209758) - Flow Cytometry
Flow Cytometry analysis of pLVX-puro-Q9BZR6-hu-Nogo Receptor/NgR/RTN4R-FL cells labelling NGR at 1×105 cell/well can bind Abbott patent anti-NGR (anti-NGR) (Ab209758), with the EC50 is 0.099 nM.

Abbott patent anti-NGR (anti-NGR) (Ab209758) - SEC
The purity of Abbott patent anti-NGR (anti-NGR) (Ab209758) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Solution Calculators

Reviews

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