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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab209876-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$109.90
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Ab209876-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$509.90
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Ab209876-5mg
|
5mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$1,399.90
|
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Ab209876-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$2,299.90
|
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Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated
| Product Name | Ab-14E1 (anti-ACVR2A) - Primary antibody, specific to ACVR2A |
|---|---|
| Synonyms | Activin A receptor type IIA antibody | Activin receptor type 2A antibody | Activin receptor type IIA antibody | Activin receptor type-2A antibody | ACTR 2 antibody | ACTR IIA antibody | ACTR-IIA antibody | ACTR2 antibody | ACTRII antibody | ACTRIIA antibo |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Biochemical and Physiological Mechanisms | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional |
| Host species | Human |
| Specificity | ACVR2A |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
Ab-14E1 (anti-ACVR2A) is rabbit polyclonal antibody targeting human ACVR2A. It can be used in research of human intestinal cancer and preeclampsia. |
| Light Chain Type | kappa |
|---|---|
| SDS-PAGE | 150 kDa |
| Purification Method | Protein A purified |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Ab-14E1 (anti-ACVR2A) (Ab209876) - ELISA
Immobilized Recombinant Hu-Activin RIIA / ACVR2A Protein, His Tag at 1.0 μg/mL can bind Ab-14E1 (anti-ACVR2A) (Ab209876) with the EC50 of 12.52 ng/mL.
Ab-14E1 (anti-ACVR2A) (Ab209876) - SEC
The purity of Ab-14E1 (anti-ACVR2A) (Ab209876) is more than 95% verified by HPLC.