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Brontictuzumab (anti-NOTCH1) - Primary antibody, specific to NOTCH1, >95%, high purity, Human IgG2SA, Antibody of notch receptor 1, Antibody of notch receptor 1

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human,Mouse
  • Isotype: Human IgG2SA
  • Conjugation: Unconjugated
In stock
Item Number
Ab175482
Grouped product items
SKU Size
Availability
Price Qty
Ab175482-100μg
100μg
10
$79.90
Ab175482-1mg
1mg
4
$389.90
Ab175482-5mg
5mg
1
$999.90
Ab175482-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,599.90

Purity≥95% (SDS-PAGE&SEC); Endotoxin Level≤1.0EU/mg; Human IgG2SA; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Brontictuzumab (anti-NOTCH1) - Primary antibody, specific to NOTCH1, >95%, high purity, Human IgG2SA, Antibody of notch receptor 1
Synonyms 9930111A19Rik antibody | AOS5 antibody | AOVD1 antibody | hN1 antibody | Lin-12 antibody | LIN12 antibody | Mis6 antibody | Motch A antibody | mT14 antibody | Neurogenic locus notch homolog protein 1 antibody | Neurogenic locus notch protein homolog antib
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity NOTCH1
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action Antibody of notch receptor 1
Product Description

来源MCE: HY-P99258;P230003402批次浓度为 8.13 mg/mL.

Product Properties

Isotype Human IgG2SA
Light Chain Type lambdaC2
SDS-PAGE 27.8 kDa (Light Chain) & 54.5 kDa (Heavy Chain), under reducing conditions; 188.9 kDa, under non-reducing conditions.
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1447814-75-6

Associated Targets(Human)

NOTCH1 Tchem Neurogenic locus notch homolog protein 1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
NOTCH1 Tchem Neurogenic locus notch homolog protein 1 (161 Activities)
Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Brontictuzumab (anti-NOTCH1) (Ab175482) - Flow Cytometry
Flow Cytometry analysis of MOLT-4 cells labelling NOTCH1 (red) with Brontictuzumab (anti-NOTCH1) (Ab175482). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Brontictuzumab (anti-NOTCH1) (Ab175482) - Flow Cytometry
Flow Cytometry analysis of Jurkat cells labelling NOTCH1 (red) with Brontictuzumab (anti-NOTCH1) (Ab175482). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Brontictuzumab (anti-NOTCH1) (Ab175482) - SEC
The purity of Brontictuzumab (anti-NOTCH1) (Ab175482) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0505429 Certificate of Analysis May 11, 2024 Ab175482
ZJ24F0505428 Certificate of Analysis May 11, 2024 Ab175482
ZJ24F0505427 Certificate of Analysis May 11, 2024 Ab175482

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