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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab175482-100μg
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100μg |
10
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$79.90
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Ab175482-1mg
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1mg |
4
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$389.90
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Ab175482-5mg
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5mg |
1
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$999.90
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Ab175482-10mg
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10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$1,599.90
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Purity≥95% (SDS-PAGE&SEC); Endotoxin Level≤1.0EU/mg; Human IgG2SA; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Brontictuzumab (anti-NOTCH1) - Primary antibody, specific to NOTCH1, >95%, high purity, Human IgG2SA, Antibody of notch receptor 1 |
|---|---|
| Synonyms | 9930111A19Rik antibody | AOS5 antibody | AOVD1 antibody | hN1 antibody | Lin-12 antibody | LIN12 antibody | Mis6 antibody | Motch A antibody | mT14 antibody | Neurogenic locus notch homolog protein 1 antibody | Neurogenic locus notch protein homolog antib |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | NOTCH1 |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | Antibody of notch receptor 1 |
| Product Description |
来源MCE: HY-P99258;P230003402批次浓度为 8.13 mg/mL.
|
| Isotype | Human IgG2SA |
|---|---|
| Light Chain Type | lambdaC2 |
| SDS-PAGE | 27.8 kDa (Light Chain) & 54.5 kDa (Heavy Chain), under reducing conditions; 188.9 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 1447814-75-6 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Brontictuzumab (anti-NOTCH1) (Ab175482) - Flow Cytometry
Flow Cytometry analysis of MOLT-4 cells labelling NOTCH1 (red) with Brontictuzumab (anti-NOTCH1) (Ab175482). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Brontictuzumab (anti-NOTCH1) (Ab175482) - Flow Cytometry
Flow Cytometry analysis of Jurkat cells labelling NOTCH1 (red) with Brontictuzumab (anti-NOTCH1) (Ab175482). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Brontictuzumab (anti-NOTCH1) (Ab175482) - SEC
The purity of Brontictuzumab (anti-NOTCH1) (Ab175482) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | May 11, 2024 | Ab175482 | |
| Certificate of Analysis | May 11, 2024 | Ab175482 | |
| Certificate of Analysis | May 11, 2024 | Ab175482 |