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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab169276-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$59.90
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Ab169276-1mg
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1mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$267.90
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Ab169276-5mg
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5mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
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$657.90
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Ab169276-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$957.90
|
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG2; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Brodalumab (anti-IL17RA) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to IL-17Ra / CD217, >95%, high purity, Human IgG2, Antibody of Interleukin 17 receptor A |
|---|---|
| Synonyms | Recombinant Brodalumab Antibody | Brodalumab | AMG 827 | KHK4827 | Brodalumab (anti-IL17RA) | Anti-IL-17Ra / CD217 Reference Antibody (brodalumab) | CANDF5 antibody | CD217 antibody | CD217 antigen antibody | CDw217 antibody | CTLA8 antibody | HIL 17R ant |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | IL-17Ra / CD217 |
| Application | ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | ANTAGONIST |
| Mechanism of action | Antibody of Interleukin 17 receptor A |
| Product Description |
Brodalumab is a human anti-interleukin-17-receptor IgG2 monoclonal antibody that can be used for the research of moderate-to-severe plaque psoriasis and rheumatoid arthritis. |
| Antibody Type | Primary antibody |
|---|---|
| Clonality | Recombinant |
| Isotype | Human IgG2 |
| Light Chain Type | kappa |
| SDS-PAGE | 144.06 kDa |
| Purification Method | Protein A purified |
| Purity | >95% |
| Source | CHO supernatant |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 1174395-19-7 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Brodalumab (anti-IL17RA) (Ab169276) - Flow Cytometry
Flow Cytometry analysis of K562 cells labelling IL17RA (red) with Brodalumab (anti-IL17RA) (Ab169276) . Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG2. Black - Unlabelled control, cells without incubation with primary antibody.
Brodalumab (anti-IL17RA) (Ab169276) - SEC
The purity of Brodalumab (anti-IL17RA) (Ab169276) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Jul 05, 2024 | Ab169276 | |
| Certificate of Analysis | Sep 28, 2023 | Ab169276 | |
| Certificate of Analysis | Sep 28, 2023 | Ab169276 |