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Brodalumab (anti-IL17RA) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to IL-17Ra / CD217, >95%, high purity, Human IgG2, Antibody of Interleukin 17 receptor A, Antibody of Interleukin 17 receptor A

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Cynomolgus monkey,Human
  • Isotype: Human IgG2
  • Conjugation: Unconjugated
In stock
Item Number
Ab169276
Grouped product items
SKU Size
Availability
Price Qty
Ab169276-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$59.90
Ab169276-1mg
1mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$267.90
Ab169276-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$657.90
Ab169276-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$957.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG2; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Brodalumab (anti-IL17RA) - Primary antibody, for ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR) various applications, specific to IL-17Ra / CD217, >95%, high purity, Human IgG2, Antibody of Interleukin 17 receptor A
Synonyms Recombinant Brodalumab Antibody | Brodalumab | AMG 827 | KHK4827 | Brodalumab (anti-IL17RA) | Anti-IL-17Ra / CD217 Reference Antibody (brodalumab) | CANDF5 antibody | CD217 antibody | CD217 antigen antibody | CDw217 antibody | CTLA8 antibody | HIL 17R ant
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity IL-17Ra / CD217
Application ELISA,Functional Assay,Flow cytometry,Kinetics (BLI),Kinetics (SPR)
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type ANTAGONIST
Mechanism of action Antibody of Interleukin 17 receptor A
Product Description

Brodalumab is a human anti-interleukin-17-receptor IgG2 monoclonal antibody that can be used for the research of moderate-to-severe plaque psoriasis and rheumatoid arthritis.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg 

Product Properties

Antibody Type Primary antibody
Clonality Recombinant
Isotype Human IgG2
Light Chain Type kappa
SDS-PAGE 144.06 kDa
Purification Method Protein A purified
Purity >95%
Source CHO supernatant
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 1174395-19-7

Associated Targets(Human)

IL17RA Tclin Interleukin-17 receptor A (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Brodalumab (anti-IL17RA) (Ab169276) - Flow Cytometry
Flow Cytometry analysis of K562 cells labelling IL17RA (red) with Brodalumab (anti-IL17RA) (Ab169276) . Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG2. Black - Unlabelled control, cells without incubation with primary antibody.

Brodalumab (anti-IL17RA) (Ab169276) - SEC
The purity of Brodalumab (anti-IL17RA) (Ab169276) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number Certificate Type Date Item
ZJ24F0707874 Certificate of Analysis Jul 05, 2024 Ab169276
ZJ23F0901155 Certificate of Analysis Sep 28, 2023 Ab169276
ZJ23F0901154 Certificate of Analysis Sep 28, 2023 Ab169276

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