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Blasticidin-S - HCl - ≥96%, high purity , CAS No.3513-03-9

COA

Grade & Purity:

≥96%

Cas Number: 3513-03-9
Molecular Weight: 458.9
MDL number: MFCD02091640
PubChem CID: 75412545

In stock

Item Number

B139600

Grouped product items
SKU	Size	Availability	Price
B139600-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$69.90
B139600-10mg	10mg	3	$119.90
B139600-25mg	25mg	3	$179.90
B139600-100mg	100mg	3	$499.90
B139600-250mg	250mg	2	$1,229.90

Broad spectrum nucleoside antibiotic

View related series

Anti-infection (2803) Bacterial-Antibiotic (3)

Basic Description

Synonyms	(2S,3S,6R)-3-[[(3S)-3-amino-5-[carbamimidoyl(methyl)amino]pentanoyl]amino]-6-(4-amino-2-oxopyrimidin-1-yl)-3,6-dihydro-2H-pyran-2-carboxylic acid;hydrochloride \| blasticidin S HCl \| (2S,3S,6R)-6-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-[(3S)-3-amino-5-
Specifications & Purity	≥96%
Biochemical and Physiological Mechanisms	Blasticidin S Hydrochloride, like puromycin, belongs to a group of cytosine amino nucleoside antibiotics. The compound blasticidin S has a wide spectrum of antimicrobial activity and acts on prokaryotic and eukaryotic organisms by inhibiting protein synth
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads This product requires cold chain shipping. Ground and other economy services are not available.
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic -refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	Blasticidin S Hydrochloride belongs to a group of cytosine amino nucleoside antibiotics. The compound Blasticidin S has a wide spectrum of antimicrobial activity and acts on prokaryotic and eukaryotic organisms by inhibiting protein synthesis. Blasticidin-S is a commonly used tool in genetic engineering. Blasticidin-S inhibits protein synthesis in both prokaryotic and eukaryotic cells. It is common method to include a gene for Blasticidin S resistance into the plasmid being inserted into the target cells, and then to apply Blasticidin S to the culture to select these cells that have acquired that immunity. The Blasticidin S gene resistance gene (BSR), found in Bacillus cereus K55-S1, has been used in multiple studies for its use as a selective compound. Another antibiotic that belongs to the family of nucleosides is puromycin Product description Blasticidin S has been used to: Study fungicidal properties, and to prevent rice blast; Used as a selection agent for transformed cells containing the resistance genes bls, bsr, or bsd. Blasticidin S has been used to select HEK293-T cells and HEK-D5 cells with TLR-2 constructs; Used to study protein synthesis at the level of peptide bond formation.

Names and Identifiers

IUPAC Name	(2S,3S,6R)-3-[[(3S)-3-amino-5-[carbamimidoyl(methyl)amino]pentanoyl]amino]-6-(4-amino-2-oxopyrimidin-1-yl)-3,6-dihydro-2H-pyran-2-carboxylic acid;hydrochloride
INCHI	InChI=1S/C17H26N8O5.ClH/c1-24(16(20)21)6-4-9(18)8-12(26)22-10-2-3-13(30-14(10)15(27)28)25-7-5-11(19)23-17(25)29;/h2-3,5,7,9-10,13-14H,4,6,8,18H2,1H3,(H3,20,21)(H,22,26)(H,27,28)(H2,19,23,29);1H/t9-,10-,13+,14-;/m0./s1
InChIKey	YQXYQOXRCNEATG-NMQKUDMSSA-N
Smiles	CN(CCC(CC(=O)NC1C=CC(OC1C(=O)O)N2C=CC(=NC2=O)N)N)C(=N)N.Cl
Isomeric SMILES	CN(CC[C@@H](CC(=O)N[C@H]1C=C[C@@H](O[C@@H]1C(=O)O)N2C=CC(=NC2=O)N)N)C(=N)N.Cl
WGK Germany	2
PubChem CID	75412545
Molecular Weight	458.9

Certificates（CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

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18 results found

Lot Number	Certificate Type	Date	Item
F2520298	Certificate of Analysis	May 15, 2025	B139600
F2520297	Certificate of Analysis	May 15, 2025	B139600
F2520299	Certificate of Analysis	May 15, 2025	B139600
F2520300	Certificate of Analysis	May 15, 2025	B139600
F2520301	Certificate of Analysis	May 15, 2025	B139600
K2420135	Certificate of Analysis	Oct 11, 2022	B139600
K2222237	Certificate of Analysis	Oct 11, 2022	B139600
K2222238	Certificate of Analysis	Oct 11, 2022	B139600
K2222163	Certificate of Analysis	Oct 11, 2022	B139600
K2222164	Certificate of Analysis	Oct 11, 2022	B139600
G2220326	Certificate of Analysis	Jun 18, 2022	B139600
G2220325	Certificate of Analysis	Jun 18, 2022	B139600
G2220324	Certificate of Analysis	Jun 18, 2022	B139600
H2409092	Certificate of Analysis	Jun 18, 2022	B139600
G2220316	Certificate of Analysis	Jun 18, 2022	B139600
B2215288	Certificate of Analysis	Jan 17, 2022	B139600
B2215315	Certificate of Analysis	Jan 17, 2022	B139600
B2215287	Certificate of Analysis	Jan 17, 2022	B139600

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Chemical and Physical Properties

Solubility	soluble in water, Acetic acid;Slightly soluble in acidified methanol.
Sensitivity	Moisture sensitive
Refractive Index	1.71
Boil Point(°C)	772.1 °C at 760 mmHg
Molecular Weight	458.900 g/mol
XLogP3
Hydrogen Bond Donor Count	7
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	9
Exact Mass	458.179 Da
Monoisotopic Mass	458.179 Da
Topological Polar Surface Area	213.000 Å²
Heavy Atom Count	31
Formal Charge	0
Complexity	795.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	4
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	2

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