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Blasticidin-S - HCl - 10mM in Water, high purity , CAS No.3513-03-9

    Grade & Purity:
  • 10mM in Water
In stock
Item Number
B423562
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B423562-1ml
1ml
Available within 8-12 weeks(?)
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$241.90

Broad spectrum nucleoside antibiotic

Basic Description

Synonyms Blasticidin S hydrochloride | blasticidin S HCl | 3513-03-9 | Blasticidin S (hydrochloride) | MFCD02091640 | BlasticidinShydrochloride | AKOS025147372 | Bla-S; Blasticidin S; Blasticidin S HCl | HY-103401 | CS-0027828 | (2S,3S,6R)-3-[[(3S)-3-amino-5-[carbamimidoyl(methyl)ami
Specifications & Purity 10mM in Water
Biochemical and Physiological Mechanisms Blasticidin S Hydrochloride, like puromycin, belongs to a group of cytosine amino nucleoside antibiotics. The compound blasticidin S has a wide spectrum of antimicrobial activity and acts on prokaryotic and eukaryotic organisms by inhibiting protein synth
Storage Temp Store at -80°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Product Description

Blasticidin S Hydrochloride belongs to a group of cytosine amino nucleoside antibiotics. The compound Blasticidin S has a wide spectrum of antimicrobial activity and acts on prokaryotic and eukaryotic organisms by inhibiting protein synthesis.
Blasticidin-S is a commonly used tool in genetic engineering. Blasticidin-S inhibits protein synthesis in both prokaryotic and eukaryotic cells. It is common method to include a gene for Blasticidin S resistance into the plasmid being inserted into the target cells, and then to apply Blasticidin S to the culture to select these cells that have acquired that immunity. The Blasticidin S gene resistance gene (BSR), found in Bacillus cereus K55-S1, has been used in multiple studies for its use as a selective compound. Another antibiotic that belongs to the family of nucleosides is puromycin

Names and Identifiers

IUPAC Name (2S,3S,6R)-3-[[(3S)-3-amino-5-[carbamimidoyl(methyl)amino]pentanoyl]amino]-6-(4-amino-2-oxopyrimidin-1-yl)-3,6-dihydro-2H-pyran-2-carboxylic acid;hydrochloride
INCHI InChI=1S/C17H26N8O5.ClH/c1-24(16(20)21)6-4-9(18)8-12(26)22-10-2-3-13(30-14(10)15(27)28)25-7-5-11(19)23-17(25)29;/h2-3,5,7,9-10,13-14H,4,6,8,18H2,1H3,(H3,20,21)(H,22,26)(H,27,28)(H2,19,23,29);1H/t9-,10-,13+,14-;/m0./s1
InChIKey YQXYQOXRCNEATG-NMQKUDMSSA-N
Smiles CN(CCC(CC(=O)NC1C=CC(OC1C(=O)O)N2C=CC(=NC2=O)N)N)C(=N)N.Cl
Isomeric SMILES CN(CC[C@@H](CC(=O)N[C@H]1C=C[C@@H](O[C@@H]1C(=O)O)N2C=CC(=NC2=O)N)N)C(=N)N.Cl
WGK Germany 2
PubChem CID 75412545
Molecular Weight 458.9

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Chemical and Physical Properties

Sensitivity Moisture sensitive
Refractive Index 1.71
Boil Point(°C) 772.1 °C at 760 mmHg
Molecular Weight 458.900 g/mol
XLogP3
Hydrogen Bond Donor Count 7
Hydrogen Bond Acceptor Count 7
Rotatable Bond Count 9
Exact Mass 458.179 Da
Monoisotopic Mass 458.179 Da
Topological Polar Surface Area 213.000 Ų
Heavy Atom Count 31
Formal Charge 0
Complexity 795.000
Isotope Atom Count 0
Defined Atom Stereocenter Count 4
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
The total count of all stereochemical bonds 0
Covalently-Bonded Unit Count 2

Solution Calculators

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