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Batoclimab (anti-FcRn) - Primary antibody, specific to FcRn (FCGRT & B2M), >95%, high purity, Human IgG1, INHIBITOR of IgG receptor FcRn large subunit p51 inhibitor, INHIBITOR of IgG receptor FcRn large subunit p51 inhibitor

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG1(K214R/L234A/L235A)
  • Conjugation: Unconjugated
In stock
Item Number
Ab170538
Grouped product items
SKU Size
Availability
Price Qty
Ab170538-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$49.90
Ab170538-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$269.90

Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0EU/mg; Human IgG1(K214R/L234A/L235A); CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name Batoclimab (anti-FcRn) - Primary antibody, specific to FcRn (FCGRT & B2M), >95%, high purity, Human IgG1, INHIBITOR of IgG receptor FcRn large subunit p51 inhibitor
Synonyms Batoclimab | FcRn | FCGRT & B2M | B2M + FCGRT | beta chain of MHC class I molecules | beta-2-microglobin | Beta-2-microglobulin | c fragment of IgG, receptor, transporter, alpha | Fc Fragment of IgG, receptor transporter, alpha | FcRn alpha chain | IgG Fc
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity FcRn (FCGRT & B2M)
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type INHIBITOR
Mechanism of action INHIBITOR of IgG receptor FcRn large subunit p51 inhibitor
Product Description

Batoclimab (anti-FcRn) is a fully humanized IgG1 monoclonal antibody targeting FcRn. Batoclimab (anti-FcRn) can be used in the research of autoimmune diseases such as myasthenia gravis and thyroid eye disease.

Product Properties

Isotype Human IgG1
Light Chain Type lambda2
SDS-PAGE 143.457 kDa
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at 2-8℃ short term (1-2 weeks). Store at -80℃ long term (36 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
CAS 2187430-05-1

Associated Targets(Human)

FCGRT Tclin IgG receptor FcRn large subunit p51 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)
B2M Tbio Beta-2-microglobulin (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

Batoclimab (anti-FcRn) (Ab170538) - SEC
The purity of Batoclimab (anti-FcRn) (Ab170538) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Solution Calculators

Reviews

Customer Reviews

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