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| SKU | Size | Availability |
Price | Qty |
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Ab170538-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
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$49.90
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Ab170538-1mg
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1mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$269.90
|
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Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0EU/mg; Human IgG1(K214R/L234A/L235A); CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated
| Product Name | Batoclimab (anti-FcRn) - Primary antibody, specific to FcRn (FCGRT & B2M), >95%, high purity, Human IgG1, INHIBITOR of IgG receptor FcRn large subunit p51 inhibitor |
|---|---|
| Synonyms | Batoclimab | FcRn | FCGRT & B2M | B2M + FCGRT | beta chain of MHC class I molecules | beta-2-microglobin | Beta-2-microglobulin | c fragment of IgG, receptor, transporter, alpha | Fc Fragment of IgG, receptor transporter, alpha | FcRn alpha chain | IgG Fc |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | FcRn (FCGRT & B2M) |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Action Type | INHIBITOR |
| Mechanism of action | INHIBITOR of IgG receptor FcRn large subunit p51 inhibitor |
| Product Description |
Batoclimab (anti-FcRn) is a fully humanized IgG1 monoclonal antibody targeting FcRn. Batoclimab (anti-FcRn) can be used in the research of autoimmune diseases such as myasthenia gravis and thyroid eye disease.
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| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | lambda2 |
| SDS-PAGE | 143.457 kDa |
| Purification Method | Protein A purified |
| Purity | >95% |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 2-8℃ short term (1-2 weeks). Store at -80℃ long term (36 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 2187430-05-1 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
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Batoclimab (anti-FcRn) (Ab170538) - SEC
The purity of Batoclimab (anti-FcRn) (Ab170538) is more than 95% verified by HPLC.