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| SKU | Size | Availability |
Price | Qty |
|---|---|---|---|---|
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Ab176456-100μg
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100μg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$129.90
|
|
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Ab176456-1mg
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1mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
|
$649.90
|
|
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Ab176456-5mg
|
5mg |
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
|
$1,629.90
|
|
|
Ab176456-10mg
|
10mg |
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
|
$2,609.90
|
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Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
| Product Name | Apamistamab (anti-PTPRC) - Primary antibody, specific to PTPRC, >95%, high purity, Human IgG1 |
|---|---|
| Synonyms | B220 antibody | CD 45 antibody | CD45 antibody | CD45 antigen antibody | CD45R antibody | GP180 antibody | L-CA antibody | LCA antibody | Leukocyte common antigen antibody | loc antibody | Ly-5 antibody | LY5 antibody | Ly5, homolog of antibody | Lyt-4 an |
| Specifications & Purity | Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA |
| Host species | Human |
| Specificity | PTPRC |
| Conjugation | Unconjugated |
| Grade | Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated |
| Product Description |
Apamistamab (anti-PTPRC) is an anti-CD45 monoclonal antibody (MoAb) with immunotherapeutic activity. |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 28.0 kDa (Light Chain) & 52.1 kDa (Heavy Chain), under reducing conditions; 198.5 kDa, under non-reducing conditions. |
| Purification Method | Protein A purified |
| Purity | >95% |
| Shape | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -80°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle. |
| CAS | 2097132-02-8 |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
Apamistamab (anti-PTPRC) (Ab176456) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling PTPRC with Apamistamab (anti-PTPRC) (Ab176456) conjugated with biotin (right panel) compared with Human IgG (Ab170213) conjugated with biotin - Isotype Control (left panel) and detected with SA-PE (rp156150).
Apamistamab (anti-PTPRC) (Ab176456) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling PTPRC (red) with Apamistamab (anti-PTPRC) (Ab176456) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, human IgG (Ab170213) conjugated with biotin. Black - Unlabelled control, cells without incubation with primary antibody.
Apamistamab (anti-PTPRC) (Ab176456) - Flow Cytometry
Flow Cytometry analysis of Jurkat cells labelling PTPRC (red) with Apamistamab (anti-PTPRC) (Ab176456). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Apamistamab (anti-PTPRC) (Ab176456) - SEC
The purity of Apamistamab (anti-PTPRC) (Ab176456) is more than 95% verified by HPLC.
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Nov 02, 2023 | Ab176456 | |
| Certificate of Analysis | Nov 02, 2023 | Ab176456 |
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