This is a demo store. No orders will be fulfilled.

AMG 108 (anti-IL-1R1) - Primary antibody, specific to IL1R1, >95%, high purity, Human IgG2

    Application:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
  • Host species: Human
  • Reactive species: Human
  • Isotype: Human IgG2
  • Conjugation: Unconjugated
In stock
Item Number
Ab177865
Grouped product items
SKU Size
Availability
Price Qty
Ab177865-100μg
100μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$109.90
Ab177865-1mg
1mg
5
$519.90
Ab177865-5mg
5mg
1
$1,399.90
Ab177865-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,239.90

Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG2; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated

Basic Description

Product Name AMG 108 (anti-IL-1R1) - Primary antibody, specific to IL1R1, >95%, high purity, Human IgG2
Synonyms CD121 antigen-like family member A | EC 3.2.2.6 | IL-1R-1 | IL-1R-alpha | IL-1RT1 | IL-1RT-1 | Interleukin-1 receptor alpha | Interleukin-1 receptor type I | p80
Specifications & Purity Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Host species Human
Specificity IL1R1
Conjugation Unconjugated
Grade Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Product Description

AMG 108 (anti-IL-1R1) is a fully humanized monoclonal antibody that targets interleukin-1 (IL-1), inhibiting the activity of IL-1a and IL-1b. It can be beneficial in treatment of osteoarthritis (OA) and rheumatoid arthritis.

Product Properties

Isotype Human IgG2
Light Chain Type kappa
SDS-PAGE 145.5 kDa
Purification Method Protein A purified
Purity >95%
Shape Liquid
Concentration See COA
Storage Temp Store at -80°C,Avoid repeated freezing and thawing
Shipped In Ice chest + Ice pads
Stability And Storage Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

IL1R1 Tclin Interleukin-1 receptor type 1 (0 Activities)
Activity Type Activity Value -log(M) Mechanism of Action Activity Reference Publications (PubMed IDs)

Mechanisms of Action

Mechanism of Action Action Type target ID Target Name Target Type Target Organism Binding Site Name References

Images

AMG 108 (anti-IL-1R1) (Ab177865) - Flow Cytometry
Flow Cytometry analysis of HeLa cells labelling IL-1R1 (red) with AMG 108 (anti-IL-1R1) (Ab177865). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

AMG 108 (anti-IL-1R1) (Ab177865) - SEC
The purity of AMG 108 (anti-IL-1R1) (Ab177865) is more than 95% verified by HPLC.

Certificates(CoA,COO,BSE/TSE and Analysis Chart)

C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number Certificate Type Date Item
ZJ23F1202218 Certificate of Analysis Dec 28, 2023 Ab177865
ZJ23F1202217 Certificate of Analysis Dec 28, 2023 Ab177865

Solution Calculators

Reviews

Customer Reviews

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.